Patents Assigned to Peter E. Nielsen
  • Peptide nucleic acids complexes of two peptide nucleic acid strands and one nucleic acid strand
    Patent number: 5986053
    Abstract: Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 16, 1999
    Assignees: Isis Pharmaceuticals, Inc., Peter E. Nielsen
    Inventors: David J. Ecker, Ole Buchardt, Michael Egholm, Peter E. Nielsen, Rolf H. Berg, Niels E. Mollegaard
  • Cleaving double-stranded DNA with peptide nucleic acids
    Patent number: 5641625
    Abstract: Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: June 24, 1997
    Assignees: ISIS Pharmaceuticals, Inc., Peter E. Nielsen
    Inventors: David J. Ecker, Ole Buchardt, Michael Egholm, Peter E. Nielsen, Rolf H. Berg, Niels E. Mollegaard