Abstract: The present invention relates to novel drugs which may be used in combating infectious micro-organisms, particularly bacteria.
Type:
Application
Filed:
October 19, 2001
Publication date:
September 18, 2003
Applicant:
Pantheco A/S and Peter E. Nielsen
Inventors:
Peter E. Nielsen, Liam Good, Henrik Frydenlund Hansen, Frederik Beck, Leila Malik, Carsten Schou, Margit Wissenbach, Birgit Kjaeldgaard Giwercman
Abstract: Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
November 16, 1999
Assignees:
Isis Pharmaceuticals, Inc., Peter E. Nielsen
Inventors:
David J. Ecker, Ole Buchardt, Michael Egholm, Peter E. Nielsen, Rolf H. Berg, Niels E. Mollegaard
Abstract: Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.
Type:
Grant
Filed:
July 2, 1993
Date of Patent:
June 24, 1997
Assignees:
ISIS Pharmaceuticals, Inc., Peter E. Nielsen
Inventors:
David J. Ecker, Ole Buchardt, Michael Egholm, Peter E. Nielsen, Rolf H. Berg, Niels E. Mollegaard