Abstract: A system and method for enabling longitudinal and radial drilling in a wellbore is described. The system and method enable an operator to perforate the casing of a wellbore with an under-reamer at the end of a drill string and, without removing the drill string from the wellbore, initiate and complete lateral jetting of the wellbore into the surrounding formation. The system utilizes a perforation tool having a ball seat, which upon seating a drop ball in the ball seat enables the perforation tool to move from a closed position to an open position thereby allowing access to the formation using a jetting tool. Prior to seating the drop ball, an under-reaming operation may be performed using a hydraulic pressure activated under-reaming tool.