Patents Assigned to Pevion Biotech, AG
  • Multiepitope vaccine for Her2/neu-associated cancers
    Patent number: 8852604
    Abstract: The present invention includes fusion peptides comprising fragments of the cancer-related protein Her2/neu, methods of preparing such fusion peptides, virosomes comprising such fusion peptides, and uses of such fusion peptides or virosomes for the prevention, treatment or amelioration of a cancer characterized by expression or over-expression of the Her2/neu protein.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: October 7, 2014
    Assignee: Pevion Biotech AG
    Inventors: Andreas Kammer, Mario Amacker, Rinaldo Zurbriggen
  • Truncated secretory aspartyl proteinase 2
    Patent number: 8715698
    Abstract: The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: May 6, 2014
    Assignees: Pevion Biotech, AG, Istituto Superiore di Sanita
    Inventors: Rinaldo Zurbriggen, Flavia de Bernardis, Antonio Cassone, Silvia Rasi
  • RSV F-protein and its use
    Patent number: 8372963
    Abstract: The present invention relates to a nucleic acid molecule, which codes for the F-protein of the respiratory syncytial virus (RSV) or a fragment thereof, for the expression in a human cell environment of codon optimized variants of said nucleic acid molecule, vectors and compositions comprising said nucleic acid molecules and the use thereof as vaccines and polypeptides coded by the nucleic acid molecules and method for the production thereof.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: February 12, 2013
    Assignees: Pevion Biotech AG, Ruhr-Universitaet Bochum
    Inventors: Thomas Grunwald, Klaus Ueberla
  • Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof
    Patent number: 8367077
    Abstract: The present invention relates to virosomes comprising hemagglutinin (HA) with improved fusion activity. Preferably, the HA comprised in said virosomes was derived from influenza virus produced in a cell line. The present invention also relates to compositions and a kit comprising the virosomes according to the invention. Further, the present invention relates to uses and methods involving said virosomes, as well as to a method for preparing same.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: February 5, 2013
    Assignee: Pevion Biotech, AG
    Inventors: Rinaldo Zurbriggen, Christian Moser, Andreas Kammer, Mario Amacker, Nicole Westerfeld, Silvia Rasi
  • Multiepitope Vaccine for Her2/Neu-Associated Cancers
    Publication number: 20120195962
    Abstract: The present invention includes fusion peptides comprising fragments of the cancer-related protein Her2/neu, methods of preparing such fusion peptides, virosomes comprising such fusion peptides, and uses of such fusion peptides or virosomes for the prevention, treatment or amelioration of a cancer characterized by expression or over-expression of the Her2/neu protein.
    Type: Application
    Filed: August 18, 2010
    Publication date: August 2, 2012
    Applicant: PEVION BIOTECH AG
    Inventors: Andreas Kammer, Mario Amacker, Rinaldo Zurbriggen