Abstract: Described a sample preparation device for preparing a sample containing particles collected onto a collection plate. The sample preparation device includes a holding device for securing the collection plate; a device for punch cutting with a sample collector, and a guiding device that includes two or more guide bores. The guiding device extends a first length along a plane x between first and second transverse sides; The guiding device includes a centerline A extending parallel to plane x dividing the guiding device into equally sized first and second halves. The two or more guide bores are asymmetrically located relative to the centerline A in the first and/or second halves.

Abstract: The disclosure pertains to a system 100 and method for collecting and measuring particles in exhaled air. The system 100 is arranged to allow for examination of the full or substantially the full volume of each exhalation of a subject.

Abstract: The disclosure pertains to a system 100 and method for collecting and measuring particles in exhaled air. The system 100 is arranged to allow for examination of the full or substantially the full volume of each exhalation of a subject.

Abstract: Particles are exhaled in the breath of animals. The nature and amounts of the particles can be indicative of certain medical conditions. They can therefore be collected, sorted according to size or mass and used in the diagnosis of one or more medical conditions. The invention provides a method and system for collecting and sorting exhaled particles and a method for diagnosis using said exhaled particles.