Patents Assigned to P. F. Medicament
  • Patent number: 4767855
    Abstract: The present invention relates to a process for the preparation of vincristine.The process for the semisynthesis of vincristine according to the present invention comprises oxidizing vinblastine or its salts with chromic acid or its salts, in ethyl acetate at a low temperature.
    Type: Grant
    Filed: June 2, 1986
    Date of Patent: August 30, 1988
    Assignee: P. F. Medicament
    Inventors: Roger Tarroux, Jacques Fahy, Philippe Hatinguais
  • Patent number: 4734403
    Abstract: The present invention relates to a membrane polysaccharide of bacterial origin having the following quantitative analytical composition:______________________________________ galactose content 66 .+-. 6% content of hexoses other than galactose <1% hexosamine (glucosamine) content 8.5 .+-. 2% amino acid content 5 .+-. 2% fatty acid content <1% nucleic acid content <0.005% protein content <0.03% and molecular weight: 90,000 .+-. 10,000.
    Type: Grant
    Filed: August 29, 1985
    Date of Patent: March 29, 1988
    Assignee: P.F. Medicament
    Inventors: Lucien Dussourd D'Hinterland, Gerard Normier, Anne-Marie Pinel
  • Patent number: 4734417
    Abstract: The invention relates to new derivatives of biphenyl primary alcohols, their preparation and use as medicaments useful in the treatment and prevention of atherosclerotic disorders. The new derivatives have the general formula ##STR1## in which X represents a halogen atom, and more particularly chlorine, bromine or fluorine in ortho or meta position,R represents an alkyl, amino alkyl, pyridyl alkyl or acyl radical and more particularly ##STR2## and acetyl.
    Type: Grant
    Filed: July 7, 1986
    Date of Patent: March 29, 1988
    Assignee: P.F. Medicament
    Inventors: Henri Cousse, Andre Delhon, Jean-Pierre Rieu, Gilbert Mouzin
  • Patent number: 4714789
    Abstract: The invention concerns halo-biphenyl tertiary alcohols of the general formula: ##STR1## in which: X is chlorine or bromine in ortho or meta position.R and R.sub.1, which may be identical or different, represent an alkyl group of low molecular weight having from 1 to 4 carbon atoms, inclusive.These new derivatives are useful as medicaments, particularly in the treatment of atherosclerosis and obesity.
    Type: Grant
    Filed: July 14, 1986
    Date of Patent: December 22, 1987
    Assignee: P. F. Medicament
    Inventors: Henri Cousse, Andre Delhon, Jean-Pierre Rieu, Jean-Francois Patoiseau
  • Patent number: 4605654
    Abstract: The present invention relates to new 2-(arylalkyloxymethyl)morpholine derivatives, the preparation thereof and their application as drugs which are useful in the treatment of disorders of the central nervous system.The 2-(arylalkyloxymethyl)morpholine derivatives according to the invention correspond to the general formula (I): ##STR1## in which: Ar denotes an aromatic group and more especially the following radicals: ##STR2## in the case where Ar denotes a phenyl radical and R denotes a hydrogen atom, an alkyl, alkoxy or halogen group, a trifluoromethyl radical, a nitro or amino group, a hydroxy group or an arylalkyloxy group.
    Type: Grant
    Filed: December 17, 1985
    Date of Patent: August 12, 1986
    Assignee: P. F. Medicament
    Inventors: Henri Cousse, Gilbert Mouzin, Jean-Pierre Rieu, Mike Briley, Antoine Stenger