Patents Assigned to Pfizer
  • 5-(alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles
    Patent number: 6838458
    Abstract: The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I: wherein the ring of the formula (R5)-A-(SOmR4), m, B, ring G, R1 through R7 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: January 4, 2005
    Assignee: Pfizer, Inc.
    Inventor: Subas M. Sakya
  • Pyrazolo[3,4-b]pyridin-6-ones as GSK-3 inhibitors
    Publication number: 20040266815
    Abstract: The present invention provides compounds of formula (I) 1
    Type: Application
    Filed: June 23, 2004
    Publication date: December 30, 2004
    Applicant: Pfizer Inc
    Inventors: Daniel W. Kung, Travis T. Wager
  • Process and ester derivatives useful for preparation of cephalosporins
    Publication number: 20040267008
    Abstract: This invention relates a process for preparing a compound of formula (I) 1
    Type: Application
    Filed: February 17, 2004
    Publication date: December 30, 2004
    Applicant: Pfizer Inc
    Inventors: Juan C. Colberg, John L. Tucker, Maurizio Zenoni, Giovanni Fogliato, Alessandro Donadelli, Isao Nagakura, Hiromasa Morita, Hideyuki Matsuo
  • Novel piperazinyl-aryloxy and piperazinyl-heteroaryloxy-n-aryl lactams
    Publication number: 20040266781
    Abstract: The present invention relates to compounds of formula I 1
    Type: Application
    Filed: June 15, 2004
    Publication date: December 30, 2004
    Applicant: Pfizer Inc
    Inventors: John Lowe, Mark A. Sanner
  • Imidazopyridine compounds having 5-HT4 receptor agonistic activity and 5-HT3 receptor antagonistic activity
    Publication number: 20040266814
    Abstract: This invention provides a compound of the formula (I): 1
    Type: Application
    Filed: April 20, 2004
    Publication date: December 30, 2004
    Applicant: Pfizer Inc
    Inventors: Hirohide Noguchi, Chikara Uchida
  • Collar containing a novel gel formulation to control arthropod infestation of animals
    Patent number: 6835386
    Abstract: The present invention provides a device, preferably a collar or ear tag, capable of the controlled, sustained release of an effective amount of an active ingredient that can protect an animal against arthropod pests, comprising a reservoir containing a novel gel formulation comprising a fatty acid, an organic solvent which is a linear aliphatic ester, a silicone-based fluid, or a combination thereof, and an active ingredient that can protect the animal against one or more arthropod pests.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: December 28, 2004
    Assignee: Pfizer Inc.
    Inventor: Luis Gutierrez
  • Macrolide antibiotics
    Patent number: 6835716
    Abstract: This invention relates to compounds of the formula wherein a, R1, R2, R3, R4, R5, R6 and X are each as defined above, and to pharmaceutically acceptable salts thereof, useful as potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating bacterial and protozoal infections by administering the compounds of formula I.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: December 28, 2004
    Assignee: Pfizer, Inc.
    Inventor: Takushi Kaneko
  • 3-Azabicyclo[3.2.1]octane derivatives
    Publication number: 20040259859
    Abstract: The subject invention relates to 3-azabicyclo[3.2.1]octane derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by opioid receptors. The subject invention also particularly relates to using such derivatives to treat certain disorders and conditions, for example irritable bowel syndrome, drug addiction, depression, anxiety, schizophrenia and eating disorders, among others.
    Type: Application
    Filed: April 14, 2004
    Publication date: December 23, 2004
    Applicant: Pfizer Inc
    Inventors: Jotham W. Coe, Stanton McHardy, Crystal G. Bashore
  • Microfluidized oil-in-water emulsions and vaccine compositions
    Publication number: 20040258701
    Abstract: This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
    Type: Application
    Filed: April 5, 2004
    Publication date: December 23, 2004
    Applicants: PFIZER INC., PFIZER PRODUCTS INC.
    Inventors: Paul J. Dominowski, Pamela Klose, Richard L. Krebs, Ramasamy Mannan
  • Morpholine dopamine agonists
    Publication number: 20040259874
    Abstract: The present invention provides for compounds of formula (I), (Ia) and (Ib) 1
    Type: Application
    Filed: December 2, 2003
    Publication date: December 23, 2004
    Applicant: Pfizer Inc.
    Inventors: Charlotte Moria Norfor Allerton, Andrew Douglas Baxter, Andrew Simon Cook, David Hepworth, Stephen Kwok-Fung Wong
  • EP4 receptor selective agonists in the treatment of osteoporosis
    Publication number: 20040259921
    Abstract: This invention is directed to EP4 receptor selective prostaglandin agonists of the Formula I, 1
    Type: Application
    Filed: September 23, 2003
    Publication date: December 23, 2004
    Applicant: Pfizer Inc
    Inventors: Kimberly O. Cameron, Bruce A. Lefker
  • Compositions and methods for treating osteoporosis and lowering cholesterol
    Publication number: 20040259886
    Abstract: This invention relates to methods, pharmaceutical compositions and kits useful in promoting bone formation and/or preventing bone loss and lowering blood cholesterol. The compositions are comprised of an estrogen agonist/antagonist as a first active component and a statin as a second active component and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration.
    Type: Application
    Filed: May 6, 2004
    Publication date: December 23, 2004
    Applicant: Pfizer Inc
    Inventors: Wesley W. Day, Andrew G. Lee, David D. Thompson
  • Cannabinoid receptor ligands and uses thereof
    Publication number: 20040259887
    Abstract: Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.
    Type: Application
    Filed: May 13, 2004
    Publication date: December 23, 2004
    Applicant: Pfizer Inc
    Inventor: Robert L. Dow
  • Ketolide antibiotics
    Patent number: 6833444
    Abstract: This invention relates to compounds of the formula 1: and to pharmaceutically acceptable salts and solvates thereof wherein X1, X2, R2, R8, R9, R10 and R11 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: December 21, 2004
    Assignee: Pfizer, Inc.
    Inventors: William T. McMillen, Takushi Kaneko
  • AveC gene product from Streptomyces hygroscopicus
    Patent number: 6833263
    Abstract: The present invention relates to polynucleotide molecules comprising sequences encoding avec gene products, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of Streptomyces avermitilis. AveC genes, homologs and partial homologs thereof are described for S. avermitilis , S. hygroscopicus, and S. griseochromogenes, respectively. The present invention further relates to vectors, host cells, and mutant strains of Streptomyces avermitilis in which the avec gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: December 21, 2004
    Assignee: Pfizer Inc.
    Inventors: Kim J. Stutzman-Engwall, Hamish McArthur, Yoshihiro Katoh
  • Corticotropin releasing factor antagonists
    Patent number: 6833378
    Abstract: Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes for preparing them. These compounds and their pharmaceutically acceptable salts are useful in the treatment disorders including CNS and stress-related disorders.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: December 21, 2004
    Assignee: Pfizer Inc
    Inventor: Yuhpyng L. Chen
  • Non-peptide GnRH agents, Pharmaceutical compositions, and methods for their use
    Patent number: 6833372
    Abstract: Non-peptide GnRH agents that inhibit the effect of gonadotropin-releasing hormone are described. Such agents are useful for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: December 21, 2004
    Assignee: Pfizer, Inc.
    Inventors: Lance C. Christie, Mark B. Anderson, Jun Feng, Yufeng Hong, Ved P. Pathak, Ranjan J. Rajapakse, Eileen V. Tompkins, Haresh Vazir, Haitao Li
  • Medication organizer system
    Publication number: 20040251165
    Abstract: A medication organizer system includes an arrangement of day of the week containers with each container divided into separate time of the day compartments. Each time of the day compartment has pictorial indicia which readily signifies a specific respective time of the day. A medication dosage instruction sheet is provided with medication/pill identifying pictorial indicia and an imprinted grid which tracts the container and compartment arrangement; the grid having juxtaposed imprinted pictorial indicia corresponding to the compartment pictorial indicia. A sheet of adhesive backed peel-off numerals is provided, whereby a peeled-off numeral corresponding to correct number of prescribed pills is adhesively inserted onto the medication dosage instruction sheet juxtaposed to the grid. The peeled-off numeral signifies the prescribed number of pills are to be taken.
    Type: Application
    Filed: June 2, 2004
    Publication date: December 16, 2004
    Applicant: Pfizer Inc
    Inventor: Nancy M. Girzaitis
  • Compounds for the treatment of female sexual dysfunction
    Publication number: 20040254153
    Abstract: A method of treating a female suffering from FSD, in particular FSAD, is described. The method comprises delivering to the female an agent that is capable of potentiating cAMP in the sexual genitalia; wherein the agent is in an amount to cause potentiation of cAMP in the sexual genitalia of the female. The agent may be admixed with a pharmaceutically acceptable carrier, diluent or excipient.
    Type: Application
    Filed: October 15, 2003
    Publication date: December 16, 2004
    Applicant: Pfizer Inc
    Inventors: Graham Nigel Maw, Christopher Peter Wayman
  • Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer
    Publication number: 20040254380
    Abstract: A process for interconverting a mixture of cis-trans isomers of a compound of formula I into the substantially pure cis isomer.
    Type: Application
    Filed: November 10, 2003
    Publication date: December 16, 2004
    Applicant: Pfizer Inc
    Inventors: John Michael Humphrey, Norma Jacqueline Tom