Abstract: The pyrazoles and pyzazolopyrimidines of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and A are as defined herein, have corticotropin releasing factor (CRF) antagonist activity. As such, they are effective In the treatment of a wide range of diseases including stress-related illnesses.
Type:
Grant
Filed:
October 30, 1997
Date of Patent:
December 21, 1999
Assignee:
Pflizer Inc.
Inventors:
William Stephen Faraci, Willard McKowan Welch, Jr.