Abstract: Pharmaceutical compositions for application topically or by suppository comprise:(a) a medicament, preferably protected from degradation by moisture by being presented in small particles of a waxy material,(b) from 5% to 40% of an inclusion compound of urea with a straight-chain aliphatic compound, preferably a fatty acid or alcohol,(c) up to 50% of an inert insoluble powder such as starch,(d) from 25% to 90% of an inert carrier, components (a), (b) and (c) being dispersed in (d).The compositions have good storage stability and a smooth texture.