Abstract: A biocomposite powder comprising 20-95% (w/w) chitin-glucan complex (CGC), and up to 50% (w/w) mannose-containing polysaccharides, wherein the biocomposite powder has a bulk density of 0.5 to 1.0 g/cm3, and wherein greater than 60% (w/w) of the particles of the biocomposite powder have a size below 212 ?m.
Type:
Grant
Filed:
May 19, 2015
Date of Patent:
August 3, 2021
Assignee:
PHARMA73, S. A.
Inventors:
Maria Filomena Andrade De Freitas, Fernando Miguel Da Silva Cruz, Maria D'Ascensão Carvalho Fernandes de Miranda Reis, Inês Da Silva Farinha
Abstract: The present invention concerns a natural biocomposite powder prepared from the biomass of yeast Pichia pastoris, comprising chitin-glucan complex (CGC) and mannose-containing polysaccharides. In a second aspect, the invention concerns the method of preparation of the natural biocomposite powder. The invention also concerns the method to obtain Pichia pastoris biomass with increased CGC content, as well as increased chitin to glucan content in the CGC. Finally, the invention concerns the use of the natural biocomposite powder, prepared from the cell wall of yeast Pichia pastoris by the method according to the invention, as excipient in the pharmaceutical, cosmetics or food industries.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
January 9, 2018
Assignee:
Pharma73, S.A.
Inventors:
Maria Filomena Andrade De Freitas, Christophe François Aimé Roca, Fernando Miguel Da Silva Cruz, Maria D'Ascensão Carvalho Fernandes De Miranda Reis, Inês Da Silva Farinha, Bárbara Ferreira Chagas, Rui Manuel Freitas Oliveira
Abstract: A biocomposite powder comprising 20-95% (w/w) chitin-glucan complex (CGC), and up to 50% (w/w) mannose-containing polysaccharides, wherein the biocomposite powder has a bulk density of 0.5 to 1.0 g/cm3, and wherein greater than 60% (w/w) of the particles of the biocomposite powder have a size below 212 ?m.
Type:
Application
Filed:
May 19, 2015
Publication date:
March 23, 2017
Applicant:
PHARMA73, S.A.
Inventors:
Maria Filomena Andrade De Freitas, Fernando Miguel Da Silva Cruz, Maria D'Ascensão Carvalho Fernandes de Miranda Reis, Inês Da Silva Farinha
Abstract: The present invention concerns a natural biocomposite powder prepared from the biomass of yeast Pichia pastoris, comprising chitin-glucan complex (CGC) and mannose-containing polysaccharides. In a second aspect, the invention concerns the method of preparation of the natural biocomposite powder. The invention also concerns the method to obtain Pichia pastoris biomass with increased CGC content, as well as increased chitin to glucan content in the CGC. Finally, the invention concerns the use of the natural biocomposite powder, prepared from the cell wall of yeast Pichia pastoris by the method according to the invention, as excipient in the pharmaceutical, cosmetics or food industries.
Type:
Application
Filed:
March 15, 2013
Publication date:
September 26, 2013
Applicant:
Pharma73, S.A.
Inventors:
Maria Filomena ANDRADE DE FREITAS, Christophe François AIMÉ Roca, Fernando Miguel DA SILVA CRUZ, Maria D'ASCENSÃO CARVALHO FERNANDES DE MIRANDA REIS, Inês DA SILVA FARINHA, Bárbara FERREIRA CHAGAS, Rui Manuel FREITAS OLIVEIRA