Abstract: A medication treatment kit and method for treating difficult-to-manage disease that require medication be administered in a particular order for effective treatment where the treatment kit has a container, a first-line treatment medication within the container, and a second-line treatment medication within the container wherein the container is configured to ensure the first-line treatment medication and the second-line treatment medication are administered in proper order where there are no other medications located side-by-side relative to the first-line treatment medication and where only the first-line treatment medication is initially presented and where the first-line treatment medication and the second-line treatment medication are medications to treat a patient having a difficult-to-manage disease.

Abstract: A medication treatment kit to ensure administration of medications in proper order for a treatment protocol requiring that the medications be taken in a particular order has a container, a lower tray or drawer located in a lower portion of the container, the lower tray or drawer containing a second-line treatment medication for a particular treatment protocol wherein the second-line treatment medication is not to be taken first by the user, and an upper tray located in an upper portion of the container, the upper tray containing a first-line treatment medication required to be taken first by the user whereby the kit has a configuration that ensures the first-line medication is used first.

Abstract: A method of treating rhinitis and rhinorrhea includes taking a daytime oral dosage unit containing a non-sedating antihistamine for treating rhinitis and an anticholinergic agent having limited capacity to cross blood-brain barrier for treating rhinorrhea, and taking a nighttime oral dosage unit containing a non-sedating anticholinergic agent that has limited capacity to cross blood-brain barrier and that is in a lower amount than the amount in the daytime oral dosage unit for treating rhinorrhea or no anticholinergic agent.