Patents Assigned to PHARMACEUTICAL INDUSTRIES LIMITED
  • Extended release liquid compositions of guanfacine
    Patent number: 10258583
    Abstract: The present invention relates to extended release liquid compositions of guanfacine. The extended release liquid compositions of the present invention are bioequivalent to marketed extended release tablet compositions of guanfacine. Said extended release liquid compositions provide substantially similar in-vitro dissolution release profile upon storage for at least seven days. Further, the extended release liquid compositions are stable. The extended release liquid compositions are in the form of ready-to-use liquid compositions or reconstituted liquid compositions. It also relates to processes for the preparation of said extended release liquid compositions.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: April 16, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Romi Barat Singh, Kalaiselvan Ramaraju, Balaram Mondal, Ashish Kumar, Suchitra Kaushik
  • Drug delivery device for pharmaceutical compositions
    Patent number: 10238803
    Abstract: The present invention relates to a dual-chamber pack with a first chamber comprising a container; and a second chamber comprising a reservoir, a biphasic connector, a plunger, and a plug with a breakable polymeric membrane. The container of the first chamber is prefilled with a pharmaceutically acceptable vehicle and the reservoir of the second chamber is prefilled with a solid composition of an active ingredient, wherein the solid composition of the active ingredient is mixed with the pharmaceutically acceptable vehicle to form a liquid pharmaceutical composition upon activation of the dual-chamber pack.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: March 26, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Ashish Kumar, Kalaiselvan Ramaraju, Romi Barat Singh, Bhupesh Kumar Mittal, Rahul Bhargava, Mohit Mittal
  • PERFUSION DOSAGE FORM
    Publication number: 20190046398
    Abstract: The present invention relates to a method for enabling hospitals or clinics to administer a dose of a drug to patients in need thereof while avoiding steps of manipulation, dilution, reconstitution, dispensing, sterilization, transfer, handling or compounding before intravenous administration. The present invention further relates to a perfusion system comprising different sets of perfusion containers, each container comprising a ready-to-infuse, stable, sterile, aqueous perfusion solution of a drug, wherein the set of perfusion containers alone or in combination provides for direct intravenous administration of a desired dose of the drug to a patient in need thereof, such that the delivered dose is equal to or within ±5% of the calculated dose.
    Type: Application
    Filed: October 12, 2018
    Publication date: February 14, 2019
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Samarth KUMAR, Prashant KANE, Subhas Balaram BHOWMICK, Kirti GANORKAR, Nishit PATEL, Ashish Anilrao DUBEWAR, Umeshkumar Mukeshbhai PATEL
  • Process for the preparation of ibrutinib
    Patent number: 10196397
    Abstract: The present invention provides processes for the preparation of ibrutinib, intermediate compounds of Formula VI and Formula VIII, and salts thereof. The processes of the present invention are commercially viable, cost-effective, environmentally friendly, and make use of inexpensive, non-hazardous, safe chemicals that are easy to handle.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: February 5, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Kapil Sharma, Bhavin Prabhudas Thanki, Mahavir Singh Khanna, Mohan Prasad
  • PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE
    Publication number: 20180369183
    Abstract: The present invention relates to pharmaceutical compositions comprising dimethyl fumarate and a pharmaceutically acceptable agent which inhibits the enzyme catalyzed degradation of dimethyl fumarate.
    Type: Application
    Filed: August 29, 2018
    Publication date: December 27, 2018
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Rajamannar THENNATI, Shirish KULKARNI, Amol KULKARNI, Vimal KANERIA, Mukesh SHARMA
  • Gastroretentive dosage system and process of preparation thereof
    Patent number: 10137094
    Abstract: The present invention relates to novel gastroretentive dosage systems, in particular, a floating capsule which releases the drug without any lag time and which remains buoyant for a sufficient period of time in the stomach. Further, the invention relates to the process of preparation thereof.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: November 27, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Varinder Kumar, Shavej Ahmad, Romi Barat Singh
  • Salts of nilotinib and polymorphs thereof
    Patent number: 10138221
    Abstract: The present invention provides novel salts of nilotinib and polymorphs thereof. The acid addition salts of nilotinib with benzenesulfonic acid, butanedisulfonic acid, 1-5-naphthalenedisulfonic acid, naphthalene-1-sulfonic acid and 1-hydroxynaph-thoic acid; hydrates and anhydrates thereof.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: November 27, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Rajamannar Thennati, Srinivasu Kilaru, Macwan Valance Surendrakumar, Dwivedi Shriprakash Dhar
  • Topical retinoid solutions
    Patent number: 10123970
    Abstract: The present invention relates to a topical solution comprising a retinoid or its pharmaceutically acceptable salts thereof and a process of preparing it.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: November 13, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Sanjay Kumar Motwani, Shashikanth P. Isloor, Vinod Arora
  • Topical pharmaceutical composition of acitretin
    Patent number: 10123987
    Abstract: The present invention relates to a topical pharmaceutical composition comprising acitretin and a process for its preparation. It also relates to a method of treating skin disorders by administering said topical pharmaceutical composition.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: November 13, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Rathinasabapathy Venkateshwaran, Vikas Jain, Vaibhav Dubey, Sumit Madan, Vinod Kumar Arora, Rajesh Rao
  • Perfusion dosage form
    Patent number: 10098813
    Abstract: The present invention relates to a method for enabling hospitals or clinics to administer a dose of a drug to patients in need thereof while avoiding steps of manipulation, dilution, reconstitution, dispensing, sterilization, transfer, handling or compounding before intravenous administration. The present invention further relates to a perfusion system comprising different sets of perfusion containers, each container comprising a ready-to-infuse, stable, sterile, aqueous perfusion solution of a drug, wherein the set of perfusion containers alone or in combination provides for direct intravenous administration of a desired dose of the drug to a patient in need thereof, such that the delivered dose is equal to or within ±5% of the calculated dose.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: October 16, 2018
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Samarth Kumar, Prashant Kane, Balaram Subhas Bhowmick, Kirti Ganorkar, Nishit Patel, Anilrao Ashish Dubewar, Mukeshbhai Umeshkumar Patel
  • Pharmaceutical compositions of dimethyl fumarate
    Patent number: 10085961
    Abstract: The present invention relates to pharmaceutical compositions comprising dimethyl fumarate and a pharmaceutically acceptable agent which inhibits the enzyme catalyzed degradation of dimethyl fumarate.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: October 2, 2018
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Rajamannar Thennati, Shirish Kulkarni, Amol Kulkarni, Vimal Kaneria, Mukesh Sharma
  • Re-useable injector device for syringe
    Patent number: 10071206
    Abstract: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: September 11, 2018
    Assignee: Teva Pharmaceutical Industries Limited
    Inventor: Toby Cowe
  • STABLE CRYSTALLINE FORM OF REGADENOSON
    Publication number: 20180208622
    Abstract: The present invention provides crystalline Form S of regadenoson which is substantially free of residual organic solvent and having an X-ray powder diffraction pattern comprising characteristic peak at 10.3, 10.8, 19.0, 21.6 and 25.5±0.2 degrees 2?.
    Type: Application
    Filed: September 10, 2016
    Publication date: July 26, 2018
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Rajamannar THENNATI, Shriprakash Dhar DWIVEDI, Arunkumar Gulabsingh YADAV, Nischalkumar Vinodbhai PATEL, Sunil Rajaram KARANKE
  • S1P3 ANTAGONISTS
    Publication number: 20180201582
    Abstract: The present invention relates to antagonists of the S1P3 receptor formula (A) as herein described and pharmaceutical compositions thereof. The compounds of formula (A) are useful in the preparation of a medicament, in particular for the treatment of Alzheimer's disease.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 19, 2018
    Applicant: Teva Pharmaceutical Industries Limited
    Inventors: Chiara Caramelli, Cesare Federico, Emanuele Gabellieri, Matteo Magnani, Iolanda Micco, Georg C. Terstappen
  • Topical solution of isotretinoin
    Patent number: 10022348
    Abstract: The present invention relates to a topical solution comprising a retinoid or its pharmaceutically acceptable salts thereof and process of preparing it.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: July 17, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Sanjay Kumar Motwani, Vaibhav Dubey, Shashikanth Isloor, Vinod Kumar Arora, Vishnu Datta Maremanda, K. K. Janakiraman, Sumit Madan, Subodh Deshmukh
  • Stable amorphous ticagrelor and a process for its preparation
    Patent number: 10017515
    Abstract: The present invention relates to a stable amorphous ticagrelor and a process for its preparation.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 10, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Nagaraju Gottumukkala, Anil Saini, Ram Thaimattam, Mahavir Singh Khanna, Mohan Prasad
  • Crystalline form of afatinib dimaleate
    Patent number: 10011591
    Abstract: The present invention provides a crystalline Form I of afatinib dimaleate, its process for preparation and pharmaceutical composition thereof, and its use in the treatment of metastatic non-small cell lung cancer.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: July 3, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Shravan Kumar Singh, Shyam Sunder Verma, Kaptan Singh, Mohan Prasad
  • Oral pharmaceutical composition of isotretinoin
    Patent number: 9999606
    Abstract: An oral pharmaceutical composition of isotretinoin and a carrier substrate, having isotretinoin in the form of gel, dispersion, solution or emulsion, which is absorbed onto the carrier substrate to form solid particles, powder, or granules. The oral pharmaceutical composition has enhanced bioavailability. A process is used for preparing the oral composition.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: June 19, 2018
    Assignee: Sun Pharmaceutical Industries Limited.
    Inventors: Rajesh Rao, Anuj Kumar Fanda, Satish Kumar Jain, Romi Barat Singh
  • PARENTERAL DOSAGE FORM OF NOREPINEPHRINE
    Publication number: 20180140563
    Abstract: The present invention relates to a ready-to-administer parenteral dosage form of norepinephrine which comprises an aqueous solution of norepinephrine, having an anti-oxidant which is not a sulfite anti-oxidant, wherein the dosage form is stable at room temperature for prolonged period of time.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 24, 2018
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Rakesh THUMMAR, Shantaram PAWAR, Prashant KANE, Subhas Balaram BHOWMICK, Samarth KUMAR, Milan Natvarbhai THAKKAR, Kandarp Maheshkumar DAVE
  • Extended release suspension compositions
    Patent number: 9962336
    Abstract: The present invention relates to a method for preparing a stable extended release suspension composition comprising multiple coated cores of an active ingredient by using a suspension base, wherein the suspension base ensures substantially similar in-vitro dissolution release profile of the active ingredient upon storage of the suspension compositions for at least seven days.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: May 8, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Romi Barat Singh, Ashish Kumar, Rajesh Srikrishan Shear, Satish Kumar Jain, Paras P. Jain