Patents Assigned to Pharmachim
  • Composition and method for treating glaucoma
    Patent number: 4923877
    Abstract: An antiglaucoma composition containing as the active component a s-/-/-2,3 dihydroxy-9,10,11-trimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo (a,f) quinolizine hydrochloride of the general formula: ##STR1## where R.sub.1 .dbd.R.sub.2 .dbd.R.sub.3 .dbd.R.sub.4 .dbd.H.dbd.R.sub.5 .dbd.R.sub.6 .dbd.R.sub.7 .dbd.CH.sub.3 OThe composition is used as an ophthalmic solution in a method for treating glaucoma by administering a therapeutic dose of 2 to 3 drops two to four times daily to a host such as a warm-blooded animal having glaucoma.
    Type: Grant
    Filed: March 3, 1988
    Date of Patent: May 8, 1990
    Assignee: Pharmachim
    Inventors: Marko T. Markov, Chavdar B. Ivanov, Deltcho G. Jelyazkov, Diana M. Mondeschka, Nikolina D. Berova, Rositza S. Rakovska, Maria G. Todorova, Diana D. Popova, Emiliya D. Slavova, Tatyana S. Zikolova, Viola M. Marinova, Radi G. Ovcharov, Petko D. Uzunov, Jossif N. Nissimov, Dobrinka G. Gentcheva