Abstract: Hyaluronic acid preparation containing an effective amount of hyaluronic acid of a molecular weight exceeding 3.times.10.sup.6 dalton, for intra-articular administration in the treatment of steroid arthropathy and progressive cartilage degeneration caused by proteoglycan degradation.

Abstract: Antibody preparation containing antibodies or fragments or derivatives thereof which possess biospecific immunotype affinity to a 4-(2-aminoethyl)imidazolyl group bound to an aliphatic carbon atom; process for manufacturing said preparation; and process for using it.In said manufacturing process, cells capable of expressing an antibody having a specificity pursuant to the invention are caused in a manner known per se to express said antibody, whereupon said antibody can be isolated and purified in a manner known per se. The antibody preparation of this invention is used as a reactant in immunological assay methods for inter alia histamine and/or methyl histamine determinations.

Abstract: Method for reperfusion therapy of a mammalian organ comprising the step of administering systemically to said organ a therapeutically active amount of an antibody preparation having specificity for a LAC-epitope that is responsible for leukocyte-endothelial cell adherence.

Abstract: The invention is concerned with a UV absorbing plastics material to be used in intraocular lenses, said material having been produced by means of incorporating in the plastics monomer mixture, prior to the polymerization thereof, a combination of chromophores selected from two groups of substances.

Abstract: Method of determining changes occurring in articular cartilage. The method involves (a) quantifying proteoglycan monomer and/or antigenic fragments thereof in a synovial fluid sample and (b) correlating the values thus obtained with progressive destructions in the articular cartilage appertaining to that sample fluid.

Abstract: A shaped article based upon cross-linked, possibly derivatized hyaluronic acid or a salt thereof is characterized in that it has a dry matter content of at least 65 percent by weight and a tensile strength of at least 2 N/cm.sup.2. The shaped article may be prepared by pressure-drying or freeze-drying a corresponding hyaluronic acid gel.

Abstract: A composition to be used in ophthalmology and containing an aqueous solution of a high molecular polymer to which has been added a polymeric dye having a molecular weight higher than 10,000.

Abstract: Method and means in/for the immunoassay determination of (I) a bacterial polypeptide capable of binding to the Fc protion of an immunoglobulin and/or (II) the high affinity antibody to said polypeptide. The characteristic feature of the method resides in using an antibody directed against the polypeptide and having antibody activity under conditions such that the immunoglobulin potentially binding to the polypeptide will substantially not bind to the polypeptide, and carrying out the immune reaction between the antibody preparation and the corresponding polypeptide epitope under such conditions.

Abstract: The present invention is concerned with azo compounds having the structure ##STR1## in which: Y is hydrogen, andX and Z are carboxy or lower alkoxycarbonyl,or the lactones or salts of said azo compound, such compounds being useful in pharmaceutical compositions and being specifically useful to inhibit 15-prostaglandin dehydrogenase (PGDH).

Abstract: The invention relates to a method of enhancing or regulating the host defense of a mammal, said method comprising administering to a mammal a therapeutically effective amount of hyaluronic acid.

Abstract: The invention is concerned with a vitreous humor substitute intended for ophthalmological uses and consisting of a gel of crosslinked hyaluronic acid and a method at retinal surgery and after vitrectomy when the vitreous humor completely or partially is exchanged for such a gel.

Abstract: Method for applying a coating of allergen on a steel tip of an instrument which is to be employed for in vivo allergy diagnostication and which has stop means adjacent to the steel tip so that solely said tip can penetrate the skin. The characteristic feature of said method is that the steel tip plus those portions of the stop means that lie in the immediate proximity of said tip are acid-pickled and then coated with allergen, to thus cause an active amount of allergen to adhere to said tip.

Abstract: An improved process of performing analysis methods based upon biospecific affinity reactions in heterogeneous systems, wherein a ligand dissolved in a liquid is reacted with a receptor immobilized on a carrier, characterized by utilizing as the carrier a porous matrix in the form of a material body having an open capillary pore system capable of absorbing and retaining liquid phase and having such limited void dimensions that the total reaction rate of the biospecific reaction or reactions within the pore system between ligand and immobilized receptor will be at least substantially independent of the diffusion of the ligand in the liquid phase. A porous matrix for use in said process has the characteristics mentioned above.

Abstract: A pharmaceutical composition containing an effective amount of an enzyme preparation which is capable of promoting decomposition of food containing meat and/or adipose tissue and is produced from aquatic animals selected from the group consisting of animals of the order Euphausiaceae and animals of the genus Mallotus, said composition being useful as a digestion promoter in gastrointestinal fluids.The invention comprises also a method for promoting degradation of food in gastrointestinal fluids by means of adding or administering said pharmaceutical composition.

Abstract: A compound having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrognase (PGDH) and having the formula ##STR1## in which R.sub.1 and R.sub.2 are hydrogen or lower alkyl;R.sub.3 is hydrogen, lower alkyl or substituted or unsubstituted phenyl;R.sub.4, R.sub.5, and R.sub.6 are hydrogen, halogen, lower alkyl, lower alkoxy, cyano, carboxy or nitro; at least one of the groups R.sub.4 to R.sub.6 being hydrogen;R.sub.7 to R.sub.11 are hydrogen, halogen, cyano, lower alkyl, trifluoromethyl, lower alkoxy, hydroxy, lower acyl, lower alkoxycarbonyl, N,N,-diloweralkyl-aminocarbonyl or N,N-loweralkylene-aminocarbonyl; and R.sub.8 and R.sub.10 may in addition be carboxy; at least two of R.sub.7 to R.sub.11 always being hydrogen; and--A-- is --CO--, --CH.sub.2 --CO--, --CH.dbd.CH--, --CH.dbd.CH--CO-- or corresponding groups in which a hydrogen atom is replaced by a lower alkyl group.The invention comprises also lactones of those compounds in which R.sub.

Abstract: The invention is concerned with a formulated preparation to be used for oral administration and containing an immunotherapeutically active amount of at least one allergen. The characteristic feature of the invention is that said formulated preparation is resistant to gastric juice and contains an antiallergic substance.

Abstract: The invention relates to an apparatus for carrying out analyses comprising at least one incubation step and at least one separation step for separating a liquid phase from a phase, which is insoluble in said liquid phase. The apparatus comprises a plurality of reaction vessels (2), making it possible to simultaneously carry out similar working sequences with reaction mixtures in the separate reaction vessels, each of which has a porous bottom (3) connected to a separate chamber (8), the reaction vessels being able to retain the reaction mixture during the incubation steps. According to the invention, there is provided a pressure regulating system, which creates a higher relative pressure in the chambers (8) than in the reaction vessels (2). This pressure difference prevents leakage from the reaction vessels to the chambers.