Publication number: 20060211694
Abstract: Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
Type:
Application
Filed:
September 14, 2005
Publication date:
September 21, 2006
Applicant:
Pharmacia Corporation, Global Patent Department
Inventors:
Balekudru Devadas, John Walker, Shaun Selness, Terri Boehm, Richard Durley, Rajesh Devraj, Brian Hickory, Paul Rucker, Kevin Jerome, Heather Madsen, Edgardo Alvira, Michele Promo, Radhika Blevis-Bal, Laura Marruto, Jeff Hitchcock, Thomas Owen, Win Naing, Li Xing, Huey Shieh, Aruna Sambandam, Shuang Liu, Ian Scott, Kevin McGee