Patents Assigned to Pharmaciaand Upjohn AB
  • Patent number: 5885486
    Abstract: The present invention is in the area of administration forms and delivery systems for drugs, vaccines and other biologically active agents. More specifically the invention is related to the preparation of suspensions of colloidal solid lipid particles (SLPs) of predominantly anisometrical shape with the lipid matrix being in a stable polymorphic modification and of suspensions of micron and submicron particles of bioactive agents (PBAs); as well as to the use of such suspensions or the lyophilizates thereof as delivery systems primarily for the parenteral administration of preferably poorly water-soluble bioactive substances, particularly drugs, and to their use in cosmetic, food and agricultural products.SLPs and PBAs are prepared by the following emulsification process:(1) A solid lipid or bioactive agent or a mixture of solid lipids or bioactive agents is melted.
    Type: Grant
    Filed: December 2, 1996
    Date of Patent: March 23, 1999
    Assignee: Pharmaciaand Upjohn AB
    Inventors: Kirsten Westesen, Britta Siekmann