Patents Assigned to Pharmacyclics, Inc. A Delaware corporation
  • INHIBITORS OF BRUTON'S TYROSINE KINASE
    Publication number: 20100324050
    Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
    Type: Application
    Filed: March 19, 2010
    Publication date: December 23, 2010
    Applicant: Pharmacyclics, Inc. A Delaware corporation
    Inventors: Lee HONIGBERG, Erik Verner, Zhengying Pan