Patents Assigned to PHARMAEXPLORER LIMITED
  • FULLY HUMANIZED ANTI-GITR ANTIBODY AND PREPARATION METHOD THEREFOR
    Publication number: 20220119541
    Abstract: Disclosed are a GITR-targeting antibody, a preparation method therefor and the use thereof. In particular, disclosed is a novel GITR-targeting chimeric antibody or a fully humanized monoclonal antibody. Also disclosed is a method for preparing the monoclonal antibody. The monoclonal antibody of the present invention can bind to a GITR antigen with a high specificity, and has a very high affinity and a significant anti-tumor activity or the like.
    Type: Application
    Filed: November 29, 2019
    Publication date: April 21, 2022
    Applicant: PHARMAEXPLORER LIMITED
    Inventors: Qianqian QI, Qing DUAN, Lile LIU, Tatchi Teddy YANG, Hu LIU, Hui MA, Xinxiu YANG, Dongxu WANG, Chaohui DAI, Mengying WANG
  • ANTI-HUMAN LAG-3 MONOCLONAL ANTIBODY AND USE THEREOF
    Publication number: 20210155689
    Abstract: Disclosed in the present invention are an antibody targeting LAG-3, a preparation method therefor and the use thereof. In particular, disclosed in the present invention is a novel monoclonal antibody targeting LAG-3. Also disclosed in the present invention is a method for the preparation of the monoclonal antibody. The monoclonal antibody of the present invention is capable of binding LAG-3 antigens with high specificity, and has very high affinity and significant activities such as anti-tumor activity.
    Type: Application
    Filed: April 2, 2019
    Publication date: May 27, 2021
    Applicants: SHANGHAI PHARMAEXPLORER CO., LTD., PHARMAEXPLORER LIMITED
    Inventors: Ningning SONG, Qing DUAN, Xiaohui SHAO, Peng WANG, Xiaojiao BIAN, Qian WANG, Peipei WEI, Yajun HUANG, Jian WU, Meiling WANG, Yuandong WANG, Lina XU, Tatchi Teddy YANG, Lile LIU
  • Anti-PCSK9 antibodies and uses thereof
    Patent number: 10858446
    Abstract: Anti-PCSK9 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as lipid disorders, metabolic diseases, hypercholesterolemia, inflammatory diseases and infectious diseases.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: December 8, 2020
    Assignee: PHARMAEXPLORER LIMITED
    Inventors: Lile Liu, Jing Gao, Xinxiu Yang, Zhiqiang Xu, Shaoping Hu, Lini Huang, Hongzhuan Gu, Yu Zhang, Yangyang Zhai, Tatchi Teddy Yang