Patents Assigned to PHARMAFLUIDICS NV
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Patent number: 12011701Abstract: A chemical reactor is implemented on a substrate. The chemical reactor has multiple ducts for transporting a fluid and/or gas during use of the chemical reactor, in which the ducts optionally include pillar structures and at least one connection duct connected between two of the multiple ducts for transporting the fluid and/or gas from one duct to another. In the connection duct, a series of individual pillar structures are positioned behind each other in the longitudinal direction of the connection duct.Type: GrantFiled: December 20, 2019Date of Patent: June 18, 2024Assignee: PharmaFluidics NVInventors: Jeff Op De Beeck, Bo Claerebout, Wim De Malsche, Paul Jacobs
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Patent number: 11724259Abstract: A method for producing a chemical reactor, wherein the chemical reactor comprises one or more effective channels which comprise pillar structures, an input connected to one of the effective channels to allow fluid/gas into the effective channels and an output connected to one of the effective channels to remove at least one component of the liquid/gas. The method comprises obtaining an initial design of the reactor, further introducing into the initial design at least a structured area positioned adjacent to an effective channel of the one or more effective channels located at the edge of the initial design, the structured area not being fluidly connected to one of the effective channels, to obtain a further design and the production of the reactor according to the further design.Type: GrantFiled: June 30, 2017Date of Patent: August 15, 2023Assignee: PHARMAFLUIDICS nvInventors: Jeff Op De Beeck, Paul Jacobs, Wim De Malsche
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Patent number: 11619587Abstract: A microfluidic device comprises a microfluidic channel having at least an inlet for receiving a fluid plug or an outlet for removing a fluid plug and a pillar based flow distributor for reorienting the fluid plug in such a way that the long axis of the fluid plug essentially is oriented perpendicular to the walls of the microfluidic channel, as opposed to its original orientation, in which the longer axis is oriented in the longitudinal direction of the narrower inlet channel. The width W of the microfluidic channel is substantially larger than the width w of the inlet or outlet channel. The microfluidic device is adapted for detecting a physical or chemical property of the fluid, the microfluidic device being configured for detecting the property in a detection area positioned across the microfluidic channel in a width direction of the microfluidic channel.Type: GrantFiled: April 27, 2018Date of Patent: April 4, 2023Assignee: PHARMAFLUIDICS NVInventors: Paul Jacobs, Wim De Malsche
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Patent number: 11491458Abstract: A method for producing a chemical reactor device based on a fluid flow comprises obtaining a substrate with a fluid channel defined by a channel wall, in which an ordered set of silicon pillar structures is positioned in the fluid channel and electrochemically anodising at least the silicon pillar structures to make the silicon pillar structures porous at least to a certain depth. After the anodising, the substrate and pillar structures are thermally treated, the treatment being carried out at a temperature, with a duration and in an atmosphere such that any silicon oxide layer formed has a thickness of less than 20 nm. The substrate and the pillar structures are further functionalized.Type: GrantFiled: September 4, 2018Date of Patent: November 8, 2022Assignee: PHARMAFLUIDICS NVInventors: Wim De Malsche, Jeff Op De Beeck, Paul Jacobs, Bo Claerebout
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Patent number: 11207682Abstract: A distributor is described for distributing a fluid flow from a smaller to a more broad fluid flow. It comprises a fluid input and a plurality of fluid outputs, and a channel structure in between the fluid input and the plurality of fluid outputs. The channel structure comprises alternatingly bifurcating channel substructures and common channel substructures wherein the substructures are arranged so that fluid exiting different channels from a bifurcating channel substructure mixes in a subsequent common channel substructure, and whereby fluid channels of the bifurcating channel substructure are arranged such that these do not contact the subsequent common channel substructure at the edges thereof.Type: GrantFiled: March 30, 2018Date of Patent: December 28, 2021Assignee: PHARMAFLUIDICS NVInventors: Gert Desmet, Sander Jespers, Sander Deridder
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Patent number: 10697942Abstract: A microfluidic device for separating a phase in a specimen has been described. This is based on a microfluidic trapping area, channels connected to it and integrated inputs and outputs connected onto the channels. An additional integrated input is provided which allows the flow in the device to be controlled and which may prevent leaking of the specimen and the phase.Type: GrantFiled: July 12, 2016Date of Patent: June 30, 2020Assignee: PHARMAFLUIDICS NVInventors: Jeff Op De Beeck, Paul Jacobs, Wim De Malsche
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Publication number: 20160001199Abstract: A chemical reactor is described comprising a substrate with a fluid channel and a set of organized pillar structures positioned in the channel. The individual pillar structures have a length in the longitudinal direction of the channel and a width in the width direction of the channel whereby their width-to-length aspect ratio is at least 7.Type: ApplicationFiled: February 5, 2014Publication date: January 7, 2016Applicant: PHARMAFLUIDICS NVInventors: Wim DE MALSCHE, Gert DESMET, Jeff OP DE BEECK, Paul JACOBS