Patents Assigned to Pharmagenesis
  • Uses of diterpenoid triepoxides as an anti-proliferative agent
    Patent number: 6949510
    Abstract: Combinations of diterpenoid triepoxides and anti-proliferative agents are used in a combination therapy to treat hyperproliferative disorders. Anti-proliferative agents of interest include agents active in killing tumor cells, as well as immunosuppressants, and a variety of other agents that reduce cellular proliferation in targeted tissues. Synergistic combinations provide for comparable or improved therapeutic effects, while lowering adverse side effects.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: September 27, 2005
    Assignees: Pharmagenesis, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Glenn D. Rosen, Edwin S. Lennox, John H. Musser
  • Anticancer treatment using triptolide prodrugs
    Patent number: 6620843
    Abstract: Water soluble triptolide prodrugs are used as anticancer agents, and are found to be more effective in vivo, at lower doses, in reducing tumor size than the widely used chemotherapeutic agents 5-fluorouracil and irinotecan.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: September 16, 2003
    Assignee: Pharmagenesis
    Inventors: John M. Fidler, Ke Li
  • Uses of diterpenoid triepoxides as an anti-proliferative agent
    Patent number: 6537984
    Abstract: Combinations of diterpenoid triepoxides and anti-proliferative agents are used in a combination therapy to treat hyperproliferative disorders. Anti-proliferative agents of interest include agents active in killing tumor cells, as well as immunosuppressants, and a variety of other agents that reduce cellular proliferation in targeted tissues. Synergistic combinations provide for comparable or improved therapeutic effects, while lowering adverse side effects.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: March 25, 2003
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Pharmagenesis
    Inventors: Glenn D. Rosen, Edwin S. Lennox, John H. Musser
  • Uses of diterpenoid triepoxides as an anti-proliferative agent
    Patent number: 6294546
    Abstract: Combinations of diterpenoid triepoxides and anti-proliferative agents are used in a combination therapy to treat hyperproliferative disorders. Anti-proliferative agents of interest include agents active in killing tumor cells, as well as immunosuppressants, and a variety of other agents that reduce cellular proliferation in targeted tissues. Synergistic combinations provide for comparable or improved therapeutic effects, while lowering adverse side effects.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: September 25, 2001
    Assignees: The Broad of Trustees of the Leland Stanford Junior University, Pharmagenesis
    Inventors: Glenn D. Rosen, Edwin S. Lennox, John H. Musser