Patents Assigned to Pharmagroup International
  • Optically active 5-oxygenated (3S)-1,3-dimethyloxindole-3-acetic acids
    Patent number: 5310935
    Abstract: The synthesis of optically active 5-oxygenated (3S)-1,3-dimethyloxindole-3-acetic acids ##STR1## and their use in the synthesis of optically active (3aS-cis)-eseroline and (3aS-cis)-N.sup.1 -benzylnoreseroline, which are important intermediates in the synthesis of compounds related to (3aS-cis)-physostigmine and carbamate analogs, and of (3aS-cis)-N.sup.1 -benzylnor- and N.sup.1 -norphysostigmine and their carbamate analogs.
    Type: Grant
    Filed: June 30, 1992
    Date of Patent: May 10, 1994
    Assignee: Pharmagroup International
    Inventors: Arnold Brossi, Danilo C. Massari, Qian-Sheng Yu