Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
Type:
Grant
Filed:
July 18, 2014
Date of Patent:
February 9, 2016
Assignee:
Pharmanest AB
Inventors:
Mark Sundberg, Arne Brodin, Nils Kallberg
Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
Type:
Grant
Filed:
March 31, 2011
Date of Patent:
September 16, 2014
Assignee:
Pharmanest AB
Inventors:
Mark Sundberg, Arne Brodin, Nils Kållberg
Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
Type:
Grant
Filed:
February 4, 2014
Date of Patent:
September 9, 2014
Assignee:
Pharmanest AB
Inventors:
Mark Sundberg, Arne Brodin, Nils Kallberg
Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
Type:
Application
Filed:
February 4, 2014
Publication date:
June 5, 2014
Applicant:
Pharmanest AB
Inventors:
Mark Sundberg, Arne Brodin, Nils Kallberg
Abstract: The present invention relates to a water-free pharmaceutical composition comprising one or more local anaesthetics in base form and which is suitable for topical administration. The composition further comprises a lipid vehicle comprising long-chain triglycerides (LCT) and at least 10% by weight of medium-chain monoglycerides (MCM) selected so the composition has an at least semi-solid appearance at the body temperature at the site of administration. The invention further relates to methods of producing and sterilizing the compositions.
Type:
Application
Filed:
March 30, 2011
Publication date:
March 6, 2014
Applicant:
PHARMANEST AB
Inventors:
Mark Sundberg, Arne Brodin, Anders Carlsson
Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
Type:
Application
Filed:
March 31, 2011
Publication date:
May 9, 2013
Applicant:
PHARMANEST AB
Inventors:
Mark Sundberg, Arne Brodin, Nils Kållberg
Abstract: The present invention relates to a gelling bioadhesive pharmaceutical composition comprising one or more local anaesthetics in base form and which is suitable for topical administration. The compositions have anisotropic organic phase behaviour that admits swelling at administration site with excess water.
Type:
Application
Filed:
March 31, 2011
Publication date:
March 28, 2013
Applicant:
PHARMANEST AB
Inventors:
Mark Sundberg, Arne Brodin, Jonas Gustafsson