Patents Assigned to Pharmanex Inc.
  • Tea catechin formulations and processes for making same
    Patent number: 6428818
    Abstract: The invention described herein encompasses methods and compositions of treating cancer or solid tumors comprising the administration of a therapeutically effective amount of catechins, a group of polyphenols found in green tea, to a mammal in need of such therapy. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC). The unique compositions of the invention contain various combinations of the catechins with reduced levels of EGCg, alone or in combination with each other or other therapeutic agents and are used to treat primary and metastatic cancers in humans. The invention also encompasses the varying modes of administration of the therapeutic compounds.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: August 6, 2002
    Assignees: Purdue Research Foundation, Pharmanex, Inc.
    Inventors: Dorothy M. Morré, D. James Morré, Raymond Cooper, Howard Sun, Qing Ye
  • Tea catechins in sustained release formulations as cancer specific proliferation inhibitors
    Patent number: 6410052
    Abstract: The invention described herein encompasses a methods and compositions of treating cancer or solid tumors comprising the administration of a therapeutically effective amount of catechins, a group of polyphenols found in green tea, to a mammal in need of such therapy. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC). The unique compositions of the invention contain various combinations of the catechins, alone or in combination with each other or other therapeutic agents and are used to treat primary and metastatic cancers in humans. The invention also encompasses the varying modes of administration of the therapeutic compounds, including a sustained release formulation which may be used as a therapeutic compound for the treatment of cancer or as a dietary supplement for the prevention of cancer.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: June 25, 2002
    Assignees: Purdue Research Foundation, Pharmanex, Inc.
    Inventors: Dorothy M. Morré, D. James Morré, Raymond Cooper, Michael N. Chang
  • Methods of preparation of bioginkgo
    Patent number: 6174531
    Abstract: The invention relates to a novel process for producing novel extracts of Ginkgo biloba leaves. The invention further relates to a process which produces novel extracts of Ginkgo biloba with an increased amount of one of the major lactones and having an improved biological activity. Further, the disclosed process allows for a controlled method to produce a desired ratio of flavone glycosides to lactones in the end product. The invention also discloses new extracts from Ginkgo biloba, particularly for oral application.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: January 16, 2001
    Assignee: Pharmanex Inc.
    Inventors: De Cheng Zhang, Zhanghun Yu, Raymond Cooper, Michael Chang