Abstract: A wound dressing (1;15;18) comprising a polyurethane film sheet (2;19) having a wound facing side (3) and an opposite side (4). The wound facing side (3) has a peripheral rim zone (5) provided with an adhesive (6) or an adhesive means (16), the peripheral rim zone (5) encircles a central sheet part (11) free of adhesive (6) or adhesive means (16), and the wound dressing (1) has a moisture vapor transmission rate of at least 1,200 g/m 2/24 hour at the adhesive-coated or adhesive-means provided rim zone (5) and a moisture vapor transmission rate at the central sheet part (12) of at least 3,000 g/m 2/24 hour. A method and production line for manufacturing various embodiments of wound dressings are also disclosed.