Patents Assigned to Pharmcia & Upjohn
  • Patent number: 5726183
    Abstract: A method of treating psoriasis with a quinoline-3-carboxamide compound comprising the structure (I) below, optionally with substituents for the hydrogen atoms shown (H.sup.1-9), or a pharmaceutically acceptable salt of said compound, where (a) ------ represents that there are two conjugated double bonds between the atoms comprised by the dashed line, (b) X.sub.1 and X.sub.2 are separately selected from an oxygen atom or an NH.sup.9 group, said X.sub.1 and X.sub.2 being bound by a single bond to the ring when attached to H.sup.7 or H.sup.8 and by a double bond when not bound to H.sup.7 or H.sup.8, (c) H.sup.1-9 are hydrogens with the provision that H.sup.9 is only present when at least one of X.sub.1 and X.sub.2 is the NH.sup.9 -group , (d) H.sup.7 and H.sup.8 are hydrogens that are attached to different atoms selected among X.sub.1, X.sub.2 and the nitrogen atoms (N) in the quinoline ring, for the manufacture of a composition intended for treating psoriasis or conditions associated with psoriasis.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: March 10, 1998
    Assignee: Pharmcia & Upjohn
    Inventors: Bo Nilsson, Agneta Svedberg, Per Gjorstrup