Patents Assigned to PHARMED ARTIS GmbH
  • Granzyme B protease variants
    Patent number: 9528101
    Abstract: The present disclosure provides novel variants of enzymes exhibiting serine protease activity; nucleic acid molecules encoding said proteases, vectors, host cells containing the nucleic acids and methods for preparation and producing such enzymes; compositions and complexes comprising at least one of the proteases; and methods for using such enzymes as a part of an immunoprotease, in particular for the treatment of cancer.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: December 27, 2016
    Assignee: PHARMED ARTIS GmbH
    Inventors: Stefan Barth, Sonja Schiffer, Grit Hehmann-Titt