Patents Assigned to Pharmed GmbH
  • Patent number: 11760737
    Abstract: The present application relates to a novel, cost-saving and efficient process for preparing 4-(2,2,3,3-tetrafluoropropyl)morpholine which serves as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: September 19, 2023
    Assignee: ADVERIO PHARM GmbH
    Inventors: Peter Fey, Sergii Pazenok, Christian Funke, Natalya Pavlovna Kolesnik, Olexandr Ivanovich Guzyr, Yuriy Grigorievich Shermolovich
  • Publication number: 20100298579
    Abstract: The field of the invention is organic synthesis, more particularly a process for preparing cannabinoids. The process described is applicable to all stereoisomers and homologues of cannabinoids. For this purpose, the present patent application provides a process for preparing the abovementioned compounds in two or three chemical synthesis steps.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 25, 2010
    Applicant: THC PHARM GMBH
    Inventors: CHRISTIAN STEUP, THOMAS HERKENROTH
  • Patent number: 6818644
    Abstract: The present invention relates to substituted piperazine derivatives of general formula wherein Ra, Rb, Rc Rf, Rg and m, n and X are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are valuable inhibitors of the microsomal triglyseride-transfer protein (MTP), medicaments containing these compounds and their use, as well as the preparation thereof.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: November 16, 2004
    Assignee: Boehringer Ingelheim Pharm GmbH & Co, KG
    Inventors: Thorsten Lehmann-Lintz, Armin Heckel, Leo Thomas, Michael Mark
  • Patent number: 6468959
    Abstract: There is provided a plural dosage form for peptide pharmaceuticals comprising a matrix of gelatin or gelatin derivative having distributed therein the peptide pharmaceutical in particular insulin, as well as, pharmaceutically conventional carriers and additives. By selection of the appropriate gelatin the pharmaceutical is liberated in the small intestine or the large intestine so that is not enzymatically degraded anymore by peptidases.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: October 22, 2002
    Assignee: ALFATEC-Pharm GmbH
    Inventors: Jens-Christian Wunderlich, Ursula Schick, Jurgen Freidenreich, Jurgen Werry
  • Patent number: 5120710
    Abstract: To improve the absorption of actve ingredients, which are not adequately bio-available on oral administration, an oral lipid medicinal composition is formed by combining a semi-solid, lipophilic component with a solid, water-soluble component. The semi-solid component is a homogeneous lipid mixture that exists as a hard fat with thermally reversible fat/liquid melting property, at least 95% of which is present in the liquid aggregate state below the body temperature of 37.degree. C. and comprises monoacyl-, diacyl-, and triacylglycerides of saturated vegetable fatty acids with chain lengths ranging from 6 to 18 carbon atoms, preferably comprising a mixture of 40 to 60% monoacyl- and diacylglycerides and 40 to 60% triacylglycerides, in which the active ingredients are either dissolved, suspended or emulsified.
    Type: Grant
    Filed: May 17, 1990
    Date of Patent: June 9, 1992
    Assignee: Pharmed GmbH
    Inventor: Rainer K. Liedtke