Patents Assigned to PHARMEDIX.CO., LTD
  • Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled receptor 119 ligand as an active ingredient
    Patent number: 9895370
    Abstract: Provided is a pharmaceutical composition for preventing or treating liver fibrosis, comprising a GPR119 ligand as an active ingredient. The composition comprising the GPR119 ligand as an active ingredient significantly inhibits the expression of collagen I, transforming growth factor ? (TGF?) and ?-smooth muscle actin (?-SMA), thereby inhibiting HSC activation, and also significantly inhibits HSC proliferation. Therefore, the composition may be effectively applied in improvement, prevention, inhibition or treatment of liver fibrosis.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: February 20, 2018
    Assignee: PHARMEDIX.CO., LTD
    Inventors: Keon Wook Kang, Kyeong Lee, Jin Won Yang