Patents Assigned to PHC Holdings Corporation
  • Patent number: 10761045
    Abstract: The present invention provides: a reagent composition having higher storage stability; a sensor involving the reagent composition; and others. According to the present invention, a specific heterocyclic compound is added to a reagent composition to improve the storage stability of the reagent composition and reduce the degree of fluctuation in current values in a sensor that utilizes reagent composition.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: September 1, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Motonori Uchiyama, Takuo Kouno
  • Patent number: 10761044
    Abstract: A reagent layer of a sensor contains as a mediator a quinone compound having a hydrophilic functional group, phenanthrenequinone, and/or a phenanthrenequinone derivative. The quinone compound has a lower redox potential than a conventional mediator, so interfering substances have less effect on detection results with this sensor.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: September 1, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Yoshifumi Takahara, Takahiro Nakaminami, Shin Ikeda
  • Publication number: 20200261026
    Abstract: A measurement method includes a first measurement in which a characteristic amount of a specific analyte in a biological fluid is measured with a biosensor. The method also includes a second measurement in which motion information of living activity is measured. Additionally, the method may include recording the motion information and the characteristic amount measured in the first measurement with the motion information and characteristic amount associated with each other.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 20, 2020
    Applicant: PHC Holdings Corporation
    Inventors: Noriyoshi TERASHIMA, Masataka NADAOKA
  • Patent number: 10736508
    Abstract: Provided is a living organism information measurement device which users can easily and reliably operate. A living organism information measurement device for acquiring living organism information and generating measurement data relating to the information is provided with a device body, and a panel detachably attached to the device body. The device body comprises a control unit which executes a plurality of functions of the device body, a living organism information measurement unit which is connected to the control unit and generates the measurement data, and a first communication unit connected to the control unit. The panel comprises a second communication unit including a memory storing predetermined information. When the panel is attached to the device body, the first communication unit receives the predetermined information from the second communication unit. The control unit selects and executes a function corresponding to the received predetermined information among the plurality of functions.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: August 11, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventor: Koji Okuyama
  • Patent number: 10731898
    Abstract: A binary refrigerating apparatus employs a refrigerant composition that has a small global-warming potential (GWP) and can be used as a refrigerant capable of achieving a low temperature of ?80° C. A refrigerant composition used as a low-temperature-side refrigerant is a refrigerant mixture including a non-azeotropic mixture in which 20% by mass or less of carbon dioxide (R744) is mixed to difluoroethylene (R1132a). A refrigerant composition used as a high-temperature-side refrigerant is a combination of: a non-azeotropic mixture comprising the refrigerant group of difluoromethane (R32), pentafluoroethane (R125), 1,1,1,2-tetrafluoroethane (R134a) and 1,1,3-trifluoro ethane (R143a); and 1,1,1,2,3-pentafluoropentene (HFO-1234ze), having a global-warming potential (GWP) of 1500 or less.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: August 4, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Jiro Yuzawa, Takashi Toyooka
  • Patent number: 10729851
    Abstract: With certain implementations, the configuration is such that a controller uses a first driver to move a pharmaceutical syringe attachment component closer to the distal end side than a needle removal position when a needle unit is attached to a pharmaceutical syringe unit or when the needle unit is removed from the pharmaceutical syringe unit, so when an injection needle is attached to the pharmaceutical syringe unit, or when the injection needle is removed from the pharmaceutical syringe unit, these operations can be executed without removing a distal end cap, which makes the device extremely convenient to use.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: August 4, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Seiji Kikuchi, Toshiaki Iio
  • Patent number: 10702503
    Abstract: Provided is a catalase inhibitor comprising a compound represented by formula (I): wherein R1 to R4 independently represent a hydrogen atom, a halogen atom, an amino group, a hydroxyl group, a carbonyl group, or a hydrocarbon group having 1 to 4 carbon atoms, wherein the hydrocarbon group may have at least one substituent selected from the group consisting of a halogen atom, an amino group, a hydroxyl group and a carbonyl group; and X? represents an anionic chemical species.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: July 7, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Keigo Haneda, Takashi Endoh
  • Patent number: 10704807
    Abstract: An ultralow binary refrigeration apparatus, which cools an enclosed space to an ultralow temperature of ?80° C. or lower to be used for storing cells or microorganisms, for example, without posing worries in regard of Ozone Depletion Potential (ODP) and Global Warming Potential (GWP), and which is excellent in refrigerant stability, can dispense with an oil separator, and enables a reduction in the amount of refrigerant, or a reduction in the power output of the compressor. The object is achieved by a binary refrigeration apparatus configured by connecting a high temperature refrigeration cycle and a low temperature refrigeration cycle via a cascade condenser, in which the high temperature refrigeration cycle is filled with propane as a refrigerant and a refrigerator oil, while the low temperature refrigeration cycle is filled with a hydrocarbon having a boiling point of ?80° C. or lower as a refrigerant, a refrigerator oil, and an oil return agent.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: July 7, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Susumu Kobayashi, Hiroyuki Satou
  • Patent number: 10704808
    Abstract: An ultra-low temperature freezer includes: an insulated case defining a storage compartment having an opening in an upper face; an insulated door capable of opening and closing the opening; a first refrigeration unit configured such that a first compressor, a first condenser, and a first decompressor are mounted on a first mounting board; a second refrigeration unit configured such that a second compressor, a second condenser, and a second decompressor are mounted on a second mounting board; a machinery compartment provided near the insulated case, and configured to house the first and second refrigeration units to be independently drawable in the horizontal direction; and a control unit, where a control circuit is mounted, configured to be drawable independently of the first and second refrigeration units, the first and second refrigeration units and the control unit being housed in the machinery compartment to be stacked in a vertical direction.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: July 7, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Yoshihiro Takahashi, Takashi Arai
  • Patent number: 10704020
    Abstract: An incubator includes: an insulated box including an incubation space surrounded by multiple inner faces; a humidifying unit that humidifies an incubation space; a first heating unit that heats a first inner face among the multiple inner faces, with electric power supplied; a second heating unit that heats a second inner face, different from the first inner face, with electric power supplied; and a control unit that controls the magnitude of electric power supplied to each of the first heating unit and the second heating unit. The control unit repeatedly changes the magnitude of electric power supplied to the first heating unit at first timing, and also repeatedly changes the magnitude of electric power supplied to the second heating unit at second timing different from the first timing.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: July 7, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Hironobu Sekine, Koichi Kobayashi
  • Patent number: 10697988
    Abstract: A container management apparatus is provided with: a container storing unit that can store a plurality of tubular sample containers one by one separately, each of the plurality of tubular sample containers being provided with a two-dimensional bar code on the bottom surface thereof, and container-identifying information being coded in the two-dimensional bar code; and a reading unit that reads the two-dimensional bar code of each of the tubular sample containers stored in the container storing unit and retrieves the container identifying information. The reading unit has, in correspondence with each storing position, an LED that irradiates the two-dimensional bar code with irradiation light and an imaging unit that receives reflection light from the two-dimensional bar code.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: June 30, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Katsuya Watanabe, Ryoichi Imanaka
  • Patent number: 10690620
    Abstract: The method includes: acquiring data a related to a temperature of a blood sample on a sensor chip, based on a dimension of a current flowing in the blood sample by applying a first voltage to the pair of electrodes in contact with the blood sample, the first voltage being set so as to reduce an effect of hematocrit on a temperature measurement result; acquiring data b related to the concentration of an analyte in the blood sample, based on a dimension of a current flowing in the blood sample by applying a second voltage that is equal to or less than the first voltage, utilizing a reaction mediated by an oxidoreductase that uses the analyte in the blood sample as a substrate; and measuring a concentration that determines the analyte concentration in the blood sample based on the data a and the data b.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: June 23, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventor: Motonori Uchiyama
  • Patent number: 10687762
    Abstract: A measurement method includes a first measurement in which a characteristic amount of a specific analyte in a biological fluid with a biosensor having a reagent surface is measured. The method also includes a second measurement in which the tilt angle or rotation angle of the reagent surface from a neutral position, or vibration applied to the reagent surface, as motion information of living activity is measured. Additionally, the method may include recording the motion information, and controlling, based on the motion information, a measurement operation of the first measurement and a recording operation of the recording.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: June 23, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Noriyoshi Terashima, Masataka Nadaoka
  • Patent number: 10675415
    Abstract: A pharmaceutical syringe unit is configured to be mounted to a pharmaceutical injection device main body and hold a pharmaceutical-filled pharmaceutical syringe, in order to mount the pharmaceutical syringe to a pharmaceutical injection device, wherein a syringe cover is configured to slide forward and backward with respect to a distal end cap by operation of the pharmaceutical injection device main body, thereby allowing movement between a needle insertion position at which insertion of an injection needle into a target is to be completed, and a needle withdrawal position at which withdrawal of the injection needle from the target is to be completed, and a guide component is configured to guide the syringe cover over a range that is greater than a distance between the needle insertion position and the needle withdrawal position.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 9, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Yukihiro Takabatake, Toshiaki Iio, Seiji Kikuchi, Yutaro Fujino
  • Patent number: 10627155
    Abstract: Disclosed is an ultra-low temperature freezer comprising a seal. The seal member has: hollow first and second air layer forming portions which are aligned in a row in a second direction between a first and second peripheral edges when a door is closed; and a first connection portion which is connected between the first and second air layer forming portions so as to form an air layer. The first connection portion has a shape that would overlap part of the first and second air layer forming portions if moved in parallel to the second direction. The outer peripheral surface of the first connection portion and the outer peripheral surfaces of the first and second air layer forming portions form first and second recessed portions extending in a first direction.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: April 21, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventor: Tadashi Okada
  • Patent number: 10605757
    Abstract: A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes, and a driving power terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: March 31, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Shoji Miyazaki, Hiroyuki Tokunaga, Yoshinobu Tokuno
  • Patent number: 10596331
    Abstract: A pharmaceutical injecting device comprises a main body case, a piston, a drive mechanism, a display component, and a controller. The body case has a cartridge holder in which a pharmaceutical syringe is installed. The piston is provided movably with respect to the pharmaceutical syringe that is installed in the cartridge holder. The drive mechanism drives the piston. The controller is electrically connected to the drive mechanism. The display component is connected to the controller. The controller has a display controller. The display controller causes the display component to display a plurality of injection sites and to display at two or more injection sites selectable displays indicating that those injection sites are suitable for injection.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: March 24, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Tsuguhiro Kondo, Seiji Kikuchi, Yasutaka Mukai
  • Patent number: 10596317
    Abstract: With the pharmaceutical injection system in an embodiment, pharmaceutical injection amount setting conditions for setting a pharmaceutical injection amount are inputted to a portable terminal (300), and the pharmaceutical injection amount setting conditions are transmitted to a health care worker-use information terminal (500). The portable terminal (300) receives the pharmaceutical injection amount set on the basis of the pharmaceutical injection amount setting conditions transmitted from the health care worker-use information terminal (500), and transmits the pharmaceutical injection amount to a pharmaceutical injection device (100). The health care worker-use information terminal (500) receives the pharmaceutical injection amount setting conditions transmitted from the portable terminal (300), and the pharmaceutical injection amount set on the basis of the pharmaceutical injection amount setting conditions is inputted.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: March 24, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventor: Katsumi Nakanishi
  • Patent number: 10598415
    Abstract: A refrigeration apparatus includes: a refrigerant circuit that condenses a refrigerant discharged from a compressor, decompresses the refrigerant with a capillary tube, and causes the refrigerant to evaporate in an evaporator to exhibit a refrigeration effect, wherein, as the refrigerant in the refrigerant circuit, a mixed refrigerant containing a first refrigerant having a boiling point in an ultralow temperature range of not less than ?89.0° C. and not more than ?78.1° C. and carbon dioxide (R744) is enclosed, and a heater that heats at least a portion of a suction pipe through which the refrigerant that returns from the evaporator to the compressor passes is provided.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: March 24, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventor: Takashi Toyooka
  • Patent number: 10571424
    Abstract: The present invention provides: a reagent composition having higher storage stability; a sensor involving the reagent composition; and others. According to the present invention, a specific heterocyclic compound is added to a reagent composition to improve the storage stability of the reagent composition and reduce the degree of fluctuation in current values in a sensor that utilizes reagent composition.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: February 25, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Motonori Uchiyama, Takuo Kouno