Patents Assigned to PHENEX DISCOVERY VERWALTUNGS-GMBH
  • Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
    Patent number: 11078168
    Abstract: The invention provides modulators of indoleamine 2,3-dioxygenase (IDO1) and their use in the prophylaxis and/or treatment of IDO1-mediated diseases. Specifically, the present invention provides compounds according to Formula (I) an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: August 3, 2021
    Assignee: Phenex Discovery Verwaltungs-GmbH
    Inventors: Christoph Steeneck, Olaf Kinzel, Simon Anderhub, Martin Hornberger, Gerald Kleymann, Thomas Hoffmann
  • OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20200352931
    Abstract: The present invention relates to novel compounds which act as modulators of indoleamine 2,3-dioxygenase (IDO1) and to the use of said compounds in the prophylaxis and/or treatment of diseases or conditions mediated by indoleamine 2,3-dioxygenase. The invention further relates to pharmaceutical compositions comprising the novel compounds.
    Type: Application
    Filed: December 12, 2018
    Publication date: November 12, 2020
    Applicant: PHENEX DISCOVERY VERWALTUNGS-GMBH
    Inventors: Christoph Steeneck, Olaf Kinzel, Simon Anderhub, Martin Hornberger, Marta Czekanska, Thomas Hoffmann
  • SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20190292160
    Abstract: The invention provides modulators of indoleamine 2,3-dioxygenase (IDO1) and their use in the prophylaxis and/or treatment of IDO1-mediated diseases. Specifically, the present invention provides compounds according to Formula (I) an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 3, 2017
    Publication date: September 26, 2019
    Applicant: PHENEX DISCOVERY VERWALTUNGS-GMBH
    Inventors: Christoph Steeneck, Olaf Kinzel, Simon Anderhub, Martin Hornberger, Gerald Kleymann, Thomas Hoffmann