Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
Type:
Application
Filed:
June 28, 2019
Publication date:
May 20, 2021
Applicant:
Phenex-FXR GmbH
Inventors:
Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
Abstract: The present invention relates to derivatives of formula (I) which bind to the liver X receptor (LXR? and/or LXR?) and act preferably as inverse agonists of LXR.
Type:
Application
Filed:
July 18, 2018
Publication date:
April 30, 2020
Applicant:
Phenex-FXR GmbH
Inventors:
Christian Gege, Manfred Birkel, Eva Hambruch, Ulrich Deuschle, Claus Kremoser
Abstract: The present invention relates to sulfonamide-, sulfinamide- or sulfonimidamide containing compounds which bind to the liver X receptor (LXRa and/or LXR?) and act preferably as inverse agonists of LXR.
Type:
Application
Filed:
April 10, 2018
Publication date:
April 16, 2020
Applicant:
Phenex-FXR GmbH
Inventors:
Christian Gege, Manfred Birkel, Eva Hambruch, Ulrich Deuschle, Claus Kremoser