Abstract: The invention relates to a medical product, with at least portions of the medical product being provided with a coating, said coating comprising a functional layer, and the functional layer containing saccharides and peptide sequences having integrin-binding motifs. The medical product proposed by the invention exhibits improved cell adherence and, at the same time, reduced thrombocyte adhesion and aggregation, which promotes ingrowth into the surrounding tissue, while the aggregation of thrombocytes and, in particular, restenosis are prevented.

Abstract: An implant (1) for influencing the blood flow in the area of aneurysms which are localized at vascular branches of blood vessels. The implant is present in an expanded state, in which it is implanted in the blood vessel, and in a diameter-reduced, stretched state, in which it is movable through the blood vessel or a catheter. The implant (1) has at least three sections (2, 3) which, at least in the expanded state, are tubular and the walls of which are composed of interwoven wires (4) or interconnected struts, with at least two tubular sections (3) branching off from a first tubular section (2). The at least three tubular sections (2, 3) are made up individually and connected to one another at one end in each case in such a way that, in the expanded state, the blood flow through the first tubular section (2) into the tubular sections (3) branching off from the first tubular section (2) is ensured.

Abstract: The invention relates to a combination implant comprising a flow diverter (1, 2) and at least one stent (3, 4), wherein the flow diverter (1, 2) and the stent (3, 4) form a functional unit (5, 6) and the radial force of the stent (3, 4) is greater than the radial force of the flow diverter (1, 2).

Abstract: A device (1) for removing thrombi from blood vessels, wherein the device (1) has an expanded state in which it is set free temporarily in the blood vessel and a compressed state in which it is introduced into and removed from the blood vessel through a microcatheter, wherein the device (1) has a proximal (2), a middle (3) and a distal portion (4), with the middle portion (3) having a substantially cylindrical structure and the proximal portion (2) being coupled to an insertion aid (5), and the distal portion (4) having a substantially cylindrical basic structure, with a constriction (6) being arranged between the middle (3) and distal portion (4), and the distal portion (4) being at least partially covered by a membrane (7). The inventive device (1) is characterized by the fact that thrombus fragments becoming detached from the thrombus to be captured are safely retained and removed from the blood vessel.

Abstract: A device (1) for introducing endovascular implants (3), which have an at least partially cylindrical design, into blood vessels, where the implant (3) is provided in an expanded state in which the implant is placed in the blood vessel, and in a compressed state, in which the implant can be introduced into the blood vessel, and the device (1) has an elongated shaft (2), the exterior of which is releasably secured to the implant (3) in the compressed state and through which the implant (3) runs.

Abstract: A substantially tubular structure with a plurality of mesh cells (3, 4) composed of struts, with two connecting struts (5, 5?), disposed at proximal mesh cells at the proximal end of the tubular structure (1) and extending in proximal direction, and being provided with a coupling member (11) disposed proximally of the tubular structure (1) with the connecting struts (5, 5?) being connected to said member, wherein the coupling member (11) being connected to a pusher/insertion wire, and wherein struts of the proximal mesh cells, the connecting struts (5, 5?), and the coupling member (11) as well as bracing struts (9) that may be arranged between the proximal mesh cells form a closed, annular structure (6), and the annular structure (6) comprising a ring marker (12) with a radiopaque material for identifying the spatial position of the annular structure (6).

Abstract: A device (1) with a stent structure (2) wherein the stent structure (2), preferably at its proximal end, is connected to an insertion aid (3), and wherein the device (1) is deployable for the treatment of a vasospasm and the stent structure (2) is designed so as to be detachable from the insertion aid (3), with at least portions of the stent structure (2) being provided with a coating and this coating comprising a functional layer, with said functional layer containing at least one sugar alcohol and/or being formed by an oligo- or polymerization of monosaccharides functionalized with polymerizable groups. Furthermore, the invention also relates to a relevant method for the treatment of vasospasms.

Abstract: A device for introducing an implant (1) into blood vessels or hollow organs of the human or animal body. The device includes an implant (1), an insertion wire (14) and a release tube (13), wherein the implant (1) is deformable so that it fits into a microcatheter (8) and expands once the external constraint of the microcatheter (8) disappears, adapting to the diameter of the blood vessel or hollow organ, wherein a holding element (2) is arranged on the insertion wire (14) and the holding element (2) has at its periphery at least one groove (3) set into the holding element (2), running along the circumference of the holding element (2) and forming tracks in the form of curved lines, wherein the implant (1) has holding wired (5) extending proximally, which are fitted into the grooves (3).

Abstract: A device for introducing an implant (1) into blood vessels or hollow organs of the human or animal body. The device includes an implant (1), an insertion wire (14) and a release tube (13), wherein the implant (1) is deformable so that it fits into a microcatheter (8) and expands once the external constraint of the microcatheter (8) disappears, adapting to the diameter of the blood vessel or hollow organ, wherein a holding element (2) is arranged on the insertion wire (14) and the holding element (2) has at its periphery at least one groove (3) set into the holding element (2), running along the circumference of the holding element (2) and forming tracks in the form of curved lines, wherein the implant (1) has holding wired (5) extending proximally, which are fitted into the grooves (3).

Abstract: A medical device substrate with a coating including a functional layer located on the substrate, with the functional layer including at least one sugar alcohol and being bonded to the substrate directly or indirectly via a functionalization of the sugar alcohol. Alternatively, the functional layer may also include other saccharides, in which case it is essential that polymerization of the saccharides takes place only upon bonding to the substrate. The inventive medical device exhibits reduced platelet adhesion and aggregation.

Abstract: An implant (6, 18) for influencing the flow of blood in the area of bifurcation aneurysms with the implant (6, 18) having a first (1, 14) and a second tubular braided section (2, 15) each having an opening (4, 5, 16, 17) in the wall, wherein the openings (4, 5, 16, 17) in the walls being produced in such a way that the wires (3) forming the braided sections (1, 2, 14, 15) are radially displaced at the positions of the openings (4, 5, 16, 17), and the first braided section (1, 14) is guided through the opening (5, 17) in the wall of the second braided section (2, 15) such that the opening (4, 16) in the wall of the first braided section (1, 14) points to the opening (5, 17) in the wall of the second braided section (2, 15).

Abstract: The invention relates to an insertion system for an implant (1) for influencing the blood flow in the region of aneurysms (22) located at vascular bifurcations. The implant (1) has two distal tubular implant portions (2) which are intended to be placed in blood vessels (21) branching off from the stem blood vessel (20) and which are connected to one another at a branching point (4). The insertion system has two sleeves (5) which are each designed to hold a distal tubular implant portion (2). The two sleeves (5) each have a distal sleeve portion (6) and the distal sleeve portions (6) each have an opening zone (7) extending in the longitudinal direction. The distal sleeve portions (6) are each adjoined proximally by a proximal portion (8), by means of which the sleeves (5) can be retracted in the proximal direction so that the opening zones (7) open and the distal tubular implant portions (2) each pass through the opening zones (7) and are released into the branching blood vessels (21).

Abstract: The invention relates to a device for the introduction of an implant (1) into blood vessels of the human body, said device comprising an implant (1), a pusher or insertion wire (14), and a tube-like sheathing (13), wherein the implant (1) is capable of being deformed inside a microcatheter in a manner that allows it to assume a shape of reduced diameter and, after omission of such external constraint exerted by the microcatheter, expand at the placement site and adapt to the blood vessel diameter, and wherein the implant (1) being provided at the proximal end with connection elements (6) attaching it to a retaining element (15) by means of which the implant (1) is coupled to the pusher wire (14), and wherein the retaining element (15) is provided with peripheral cutouts (16) into which the connecting elements (6) are fitted, with the tube-like sheathing (13) being drawn in a form-closed manner over the retaining element (15) with fitted connection elements (6) such that the connection elements (6) are secured

Abstract: A device for introducing an implant (1) into blood vessels or hollow organs of the human or animal body. The device includes an implant (1), an insertion wire (14) and a release tube (13), wherein the implant (1) is deformable so that it fits into a microcatheter (8) and expands once the external constraint of the microcatheter (8) disappears, adapting to the diameter of the blood vessel or hollow organ, wherein a holding element (2) is arranged on the insertion wire (14) and the holding element (2) has at its periphery at least one groove (3) set into the holding element (2), running along the circumference of the holding element (2) and forming tracks in the form of curved lines, wherein the implant (1) has holding wired (5) extending proximally, which are fitted into the grooves (3).

Abstract: An occlusive implant for bifurcation aneurysms (A), with the implant (1) being in an expanded state in which it is implanted in the blood vessel and in a contracted state in which it is movable through the blood vessel, with the implant (1) having a proximal fixing section (3) by means of which the implant (1) can be secured to the wall of a blood vessel, a distal section (5) where the implant (1) in expanded state is radially widened relative to the fixing section (3) and which is intended for placement in or in front of the aneurysm (A), and having a transition section (4) located between the fixing section (3) and the distal section (5), wherein fixing section (3) is attached to an delivery wire (2) in a detachable manner and wherein the transition section (4) has a second detachment point (7) which enables the distal section (5) to be detached.

Abstract: A device for introducing an implant (1) into blood vessels or hollow organs of the human or animal body. The device includes an implant (1), an insertion wire (14) and a release tube (13), wherein the implant (1) is deformable so that it fits into a microcatheter (8) and expands once the external constraint of the microcatheter (8) disappears, adapting to the diameter of the blood vessel or hollow organ, wherein a holding element (2) is arranged on the insertion wire (14) and the holding element (2) has at its periphery at least one groove (3) set into the holding element (2), running along the circumference of the holding element (2) and forming tracks in the form of curved lines, wherein the implant (1) has holding wired (5) extending proximally, which are fitted into the grooves (3).

Abstract: A device (1) for introducing endovascular implants (3), which have an at least partially cylindrical design, into blood vessels, where the implant (3) is provided in an expanded state in which the implant is placed in the blood vessel, and in a compressed state, in which the implant can be introduced into the blood vessel, and the device (1) has an elongated shaft (2), the exterior of which is releasably secured to the implant (3) in the compressed state and through which the implant (3) runs.

Abstract: A device (1) for removing thrombi from blood vessels, wherein the device (1) has an expanded state in which it is set free temporarily in the blood vessel and a compressed state in which it is introduced into and removed from the blood vessel through a microcatheter, wherein the device (1) has a proximal (2), a middle (3) and a distal portion (4), with the middle portion (3) having a substantially cylindrical structure and the proximal portion (2) being coupled to an insertion aid (5), and the distal portion (4) having a substantially cylindrical basic structure, with a constriction (6) being arranged between the middle (3) and distal portion (4), and the distal portion (4) being at least partially covered by a membrane (7). The inventive device (1) is characterized by the fact that thrombus fragments becoming detached from the thrombus to be captured are safely retained and removed from the blood vessel.

Abstract: An implant (1) to be used for the occlusion of bifurcation aneurysms, with the implant (1) having an expanded state in which it is implanted in the blood vessel (Z) and a contracted state in which it is movable through the blood vessel (Z) and a proximal fixing section (3) a distal section (5) where the implant (1) is radially widened relative to the fixing section (3) and which is intended for placement in or in front of the aneurysm (A), and a transition section (4) located between the fixing section (3) and the distal section (5), wherein the implant (1). The implant is composed of interconnected or intersecting filaments (10) originating from the fixing section (3) or distal section (5) which meet centrally in the transition section (4), wherein the filaments (10) in the transition section (4) at least to some extent pass through a sleeve (7).

Abstract: A medical device substrate with a coating including a functional layer located on the substrate, with the functional layer including at least one sugar alcohol and being bonded to the substrate directly or indirectly via a functionalization of the sugar alcohol. Alternatively, the functional layer may also include other saccharides, in which case it is essential that polymerization of the saccharides takes place only upon bonding to the substrate. The inventive medical device exhibits reduced platelet adhesion and aggregation.