Abstract: The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a 19-nor pregnane steroid, or a pharmaceutical composition containing a vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
August 11, 1998
Assignee:
Pherin Pharmaceuticals
Inventors:
Clive L. Jennings-White, David L. Berliner, Nathan William Adams