Patents Assigned to Phigenix, Inc
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110318338
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: May 26, 2011
    Publication date: December 29, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • Targeting PAX2 for the treatment of breast cancer
    Patent number: 8080534
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the certain embodiments, the method of inhibiting expression of PAX2 is to administrate the subject a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 or by increasing expression of DEFB1 is also provided.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: December 20, 2011
    Assignee: Phigenix, Inc
    Inventor: Carlton D. Donald
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110243937
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: May 26, 2011
    Publication date: October 6, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING, AND PREVENTING PROSTATE CONDITIONS
    Publication number: 20110229492
    Abstract: Disclosed are compositions and methods for diagnosing, preventing, and treating prostate cancer and prostate intraepithelial neoplasia (PIN).
    Type: Application
    Filed: February 10, 2011
    Publication date: September 22, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110229467
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: April 29, 2011
    Publication date: September 22, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110229468
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: April 29, 2011
    Publication date: September 22, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110223161
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: May 24, 2011
    Publication date: September 15, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. Donald
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110223162
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB 1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: May 24, 2011
    Publication date: September 15, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. Donald
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110212089
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 1, 2011
    Applicant: Phigenix, Inc.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110206666
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: March 25, 2011
    Publication date: August 25, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20110206665
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
    Type: Application
    Filed: March 25, 2011
    Publication date: August 25, 2011
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20100209421
    Abstract: The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the certain embodiments, the method of inhibiting expression of PAX2 is to administrate the subject a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 or by increasing expression of DEFB1 is also provided.
    Type: Application
    Filed: February 18, 2010
    Publication date: August 19, 2010
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD
  • COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING, AND PREVENTING PROSTATE CONDITIONS
    Publication number: 20100029560
    Abstract: Disclosed are compositions and methods for diagnosing, preventing, and treating prostate cancer and prostate intraepithelial neoplasia (PIN).
    Type: Application
    Filed: January 16, 2008
    Publication date: February 4, 2010
    Applicant: PHIGENIX, INC
    Inventor: Carlton D. Donald
  • DETECTING PAX2 FOR THE DIAGNOSIS OF BREAST CANCER
    Publication number: 20100029504
    Abstract: A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin-1 gene (PAX2-to-DEFB1) expression ratio (the “Donald Predictive Factor” or “DPF”) in cells obtained from the breast of the subject, wherein the PAX2-to-DEFB1 expression ratio is correlated with breast conditions. Also disclosed is a kit for monitoring breast conditions and determining drug resistance.
    Type: Application
    Filed: August 24, 2009
    Publication date: February 4, 2010
    Applicant: PHIGENIX, INC.
    Inventor: Carlton D. DONALD