Abstract: A method of treating or preventing a skin disorder caused by at least one of excessive sebum production and abnormal keratinocyte proliferation, the method comprising topically administering to a region of the skin of a human affected by or susceptible to a skin disorder caused by at least one of excessive sebum and abnormal keratinocyte proliferation, a composition comprising anionic salicylate in an amount effective to reduce or stop the occurrence or delay the occurrence of at least one of the excessive sebum production and abnormal keratinocyte proliferation.