Patents Assigned to Philogen S.p.A.
  • ANTIGEN ASSOCIATED WITH RHEUMATOID ARTHRITIS
    Publication number: 20100260707
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the detection and treatment of rheumatoid arthritis.
    Type: Application
    Filed: October 27, 2008
    Publication date: October 14, 2010
    Applicant: PHILOGEN S.P.A.
    Inventors: Manuela Kaspar, Kathrin Schwager, Eveline Trachsel
  • Process for selecting anti-angiogenesis antibody fragments, anti-angiogenesis antibody fragments thus obtained and their use
    Patent number: 7723269
    Abstract: The invention describes a process for filter selection of anti-angiogenesis antibody fragments from a large combinatorial repertoire; the invention further relates to the anti-angiogenesis antibody fragments thus obtained.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: May 25, 2010
    Assignee: Philogen, S.p.A.
    Inventor: Leonardo Giovannoni
  • Antibodies Against Tenascin-C
    Publication number: 20080056997
    Abstract: Specific binding members against extracellular matrix protein tenascin-C, especially scFv antibody molecules against domain A1, domain C and domain D of tenascin-C. Anti-tenascin-C specific binding members conjugated with labels, cytotoxic molecules or cytokines. Use of anti-tenascin-C specific binding members in diagnosis and treatment, especially of cancer.
    Type: Application
    Filed: October 31, 2005
    Publication date: March 6, 2008
    Applicant: PHILOGEN S.P.A.
    Inventors: Simon Brack, Michela Silacci, Dario Neri
  • Antibodies to the ED-B domain of fibronectin, their construction and uses
    Patent number: 7273924
    Abstract: A specific binding member is specific for and binds directly to the ED—B oncofoetal domain of fibronectin (FN).
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: September 25, 2007
    Assignee: Philogen S.p.A.
    Inventors: Dario Neri, Barbara Carnemolla, Luciano Zardi, Gregory Paul Winter
  • Tenascin-C isoform as marker for neoplasias
    Patent number: 7109301
    Abstract: Diagnostic method for the identification of human neoplasias based on the determination of the CTN-C isoform of TN-C, fragments antibodies and their conjugates used in said method, and their therapeutic use.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: September 19, 2006
    Assignee: Philogen S.p.A.
    Inventor: Luciano Zardi