Patents Assigned to PHOSIMMUNE, INC.
  • CLASS I MHC PHOSPHOPEPTIDES FOR CANCER IMMUNOTHERAPY AND DIAGNOSIS
    Publication number: 20130259883
    Abstract: A set of phosphorylated peptides are presented by HLA A*0101, A*0201, A*0301, B*4402, B*2705, B*1402, and B*0702 on the surface of melanoma cells. They have the potential to (a) stimulate an immune response to the cancer, (b) to function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) to facilitate antibody recognition of the tumor boundaries in surgical pathology samples, and (d) act as biomarkers for early detection of the disease. Phosphorylated peptides are also presented for other cancers.
    Type: Application
    Filed: May 24, 2011
    Publication date: October 3, 2013
    Applicant: PHOSIMMUNE, INC.
    Inventors: Donald F. Hunt, Jeffrey Shabanowitz, Jennifer Cottine, Ann M. English, Andrew Norris, Victor H. Engelhard, Mark Cobbold, Kara L. Cummings, Angela Zarling, Rebecca C. Obeng, Jie Qian