Patents Assigned to PHOSPLATIN THERAPEUTICS LLC
  • Phosphaplatin Compounds as Immuno-Modulatory Agents and Therapeutic Uses Thereof
    Publication number: 20210121434
    Abstract: Use of (pyrophosphato)platinum(II) or platinum(IV) complexes (“phosphaplatins”), especially 1,2-cyclohexanediamine(pyrophosphato) platinum(II), as immunogenic cell death (ICD) inducing agents and their combination with immune checkpoint protein inhibitors for treatment of cancers, and the mechanistic rationale for the methods thereof, are disclosed.
    Type: Application
    Filed: September 7, 2018
    Publication date: April 29, 2021
    Applicant: Phosplatin Therapeutics LLC
    Inventors: Tyler Ames, Matthew Price
  • Phosphaplatin Liquid Formulations
    Publication number: 20200323810
    Abstract: Pharmaceutical compositions of phosphaplatin compounds, in particular buffered stable liquid formulations of pyrodach-2 ready for use in the treatment of various cancers, and methods of preparation are disclosed.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 15, 2020
    Applicant: Phosplatin Therapeutics LLC
    Inventors: Wayne D. Luke, Tyler Ames
  • Phosphaplatin compounds as therapeutic agents for treatment of bone or blood cancers
    Patent number: 10668080
    Abstract: Use of (pyrophosphato)platinum(II) or (pyrophosphato)platinum(IV) complexes (“phosphaplatin compounds”), especially (R,R)-1,2-cyclohexanediamine-(dihydrogen pyrophosphato)platinum(II) (or “PT-112”), as therapeutic agents for treatment of bone and blood cancers, or cancers that metastasize to bones, and methods thereof, are disclosed.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: June 2, 2020
    Assignee: Phosplatin Therapeutics LLC
    Inventors: Matthew Price, Tyler Ames
  • Synthetic and Purification Methods for Phosphaplatin Compounds and Uses Thereof
    Publication number: 20140288321
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 25, 2014
    Applicant: PHOSPLATIN THERAPEUTICS LLC
    Inventors: Wayne D. Luke, Steffen Jost
  • Synthetic Method for Phosphaplatin Compounds
    Publication number: 20140024848
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Application
    Filed: September 20, 2013
    Publication date: January 23, 2014
    Applicant: PHOSPLATIN THERAPEUTICS LLC
    Inventors: Wayne D. Luke, Steffen Jost