Patents Assigned to Photochemical Co., Ltd.
  • Patent number: 6746663
    Abstract: The present invention provides the porphyrin compound which is used for photodynamic diagnosis and/or treatment for animals, and the photodynamic diagnostic and/or therapeutic agent for animals.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: June 8, 2004
    Assignee: Photochemical Co., Ltd.
    Inventors: Isao Sakata, Susumu Nakajima, Yoshinori Nakae
  • Patent number: 6548045
    Abstract: The present invention provides the porphyrin compound having nitroimidazole in the molecule, which is used for diagnosis and/or treatment of cancer in magnetic resonance imaging (MRI) and/or radiotherapy as well as for DDS therapy. The porphyrin compound of the present invention shows no phototoxicity, and represented by the following formula: [wherein, R1 and R2 are —CH═CH2 or —CH(CH3)—OH, —CH(CH3)—O—(CH2)n—NH—Ra; R3 is hydrogen atom or —CO—(CH2)m—COOH; and M is transition metal of Mn, Fe, Co or Cu], (in which, Ra is hydrogen atom or the group represented by the following formula: n and m are the integer 2 or 3), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: April 15, 2003
    Assignee: Photochemical Co., Ltd.
    Inventors: Isao Sakata, Susumu Nakajima, Yoshinori Nakae
  • Patent number: 6063777
    Abstract: The present invention provides an iminochlorin aspartic acid derivative represented by the following formula (I): ##STR1## Wherein Asp represents an aspartic acid residue, or a pharmaceutically acceptable salt thereof. The compound of the present invention is useful as a photosensitizer for photophysico-chemical diagnosis and therapy of cancer, because it has a high accumulability to cancerous cells, reactivity to external energy and a cancerous cell destroying effect which is effective even against cancers developing in deep site, while it is rapidly excreted from normal cells and therefore causes no damage thereto.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: May 16, 2000
    Assignees: Wyeth Lederle Japan, Ltd., Photochemical Co., Ltd.
    Inventors: Muneo Hikida, Masahiko Mori, Isao Sakata, Susumu Nakajima, Hiroyuki Takata