Abstract: The present disclosure is directed to instruments and methods that provide one or more stimulations with multiple fibers and multiple imaging implants inserted in a subject for capturing images from one or more regions of the subject's brain. The microendoscope can include a single spatial light modulator or multiple spatial light modulators, a furcated imaging fiber bundle with multiple fibers, multi-implants coupled to a subject for multi-implant patterned brain imaging and stimulation. Both the single spatial light modulator and multiple spatial light modulators are capable to project optical patterns to different imaging fibers and thereby stimulate multiple regions of the brain.

Abstract: Embodiments of the present disclosure are directed to optical instruments and methods for enhancing high-contrast spatial light modulation with cascaded spatial light modulators where a first spatial light modulator displays a first spatial pattern that subsequent cascaded one or more spatial light modulators would calibrate and align with the first spatial pattern, thereby increasing the device contrast ratio of the output pattern displayed by the cascaded spatial light modulators. A relay optics is positioned somewhere between two spatial light modulators for imaging a spatial pattern from one spatial light modulator to another spatial light modulator. In addition, a light source generating an illumination to the first spatial light modulator. A projection lens receives the output pattern from an output of the cascaded spatial light modulators and imaged the output pattern to a required distance at a required magnification by a projection lens.

Abstract: A system and method for providing a fiber array light source with individually controlled multiple-wavelength outputs are disclosed. A single spatial light modulator (SLM) outputs an image light of a first wavelength and an image light of a second wavelength. An overlap image is produced based on the image light of the first and second wavelengths. A fiber array receives light associated with the overlap image so that each individual optical fiber in the fiber array corresponds to multiple pixels on the SLM.

Abstract: A system and method for multiplexing multiple images of different colors using only a single spatial light modulator (SLM) are disclosed. In the disclosed system, a first dichroic beam splitter receives an image light of first and second wavelengths from the SLM, and reflects the image light of the first wavelength towards a first mirror and an image light of the second wavelength towards a second mirror. The first mirror reflects the image light of the first wavelength at a first angle, and the second mirror reflects the image light of the second wavelength at a second angle. Further, the system includes a second dichroic beam splitter that receives the image light of the first wavelength from the first mirror and the image light of the second wavelength from the second mirror, and recombines the image light of the first and second wavelengths to produce an overlap image.

Abstract: Broadband light source systems, devices, and methods with a tunable spectrum are described by multiplexing a plurality of light sources, such as LEDs, with thin-film filters or diffraction gratings. A plurality of light sources with different or same wavelengths are multiplexed together to construct a combined broadband light source. A diffraction grating diffracts light beams from the plurality of light sources to a slit-shaped aperture, depending on selected light sources, the relative positions of the light sources to the slit-shaped aperture, and the type of grating to produce a tunable spectrum.

Abstract: Systems and methods are described employing a first lens array and a second lens array that are separated by one focal length that receives a plurality of colors signals from an X-prism and transmits to a condenser for overlapping lenslet images onto a display panel, such as a LCOS or LCD display panel. The first lens array includes a plurality of lenslets where each lenslet in the first lens array corresponds with each lenslet in a plurality of lenslets in the second lens array. The lenslets can be either refractive, defractive, or a combination of refractive and defractive.