Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
Type:
Grant
Filed:
July 28, 2016
Date of Patent:
February 25, 2020
Assignee:
PhotonMD, Inc.
Inventors:
Nicholas William Medendorp, Jr., Katelyn P. Reighard, Gerald H. Negley, Nathan Stasko
Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
Type:
Grant
Filed:
July 28, 2016
Date of Patent:
January 7, 2020
Assignee:
PhotonMD, Inc.
Inventors:
Nathan Stasko, Nicholas William Medendorp, Jr., Gerald H. Negley, Katelyn P. Reighard
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