Abstract: The detailed characteristics of the red fluorescence of the human lens—that occurs at the seventh decade of life—is recognized as an example of evolutionary photobiomodulation for repair of the retina, and then used as a paradigm for extending current parametric values for reproducible photobiomodulation. The new photobiomodulation parameters involve relative intensities for wavelength bands within the range of 600 nm to 900 nm.

Abstract: The detailed characteristics of the red fluorescence of the human lens—that occurs at the seventh decade of life—is recognized as an example of evolutionary photobiomodulation for repair of the retina, and then used as a paradigm for extending current parametric values for reproducible photobiomodulation. The new photobiomodulation parameters involve relative intensities for wavelength bands within the range of 600 nm to 900 nm.

Abstract: According to the present invention, light filters are disclosed that provide photoprotection and contain fluorescent agents in that have fluorescence emission in the near infrared region of wavelengths to effect photobiological modulation (PBM) of human cells when the cells are exposed to sunlight or any artificial lighting. The fluorescent agents include endogenous compounds. The light filters include ophthalmic lenses, skin care products with or without transparent substrate and any products that are used to filter light. When used in connection with ophthalmic lenses, the ophthalmic lense provides photoprotection and photobiological modulation to the human eye.

Abstract: An ophthalmic lens comprising a clear, non-tinted, solid plastic substrate and a dye suitable for undergoing fluorescence upconversion wherein said dye absorbs light in the near infrared region from 850 nm to 2500 nm and emit light in the shorter wavelength region from 650 nm to 850 nm thereby providing photobiomodulation to the eye.

Abstract: A compound, composition, and method for the protection of skin from the harmful effects of radiation, and particularly the harmful effects of high energy visible (HEV) radiation, are disclosed. The compound is a melanin derivative that can be formulated into compositions containing the melanin derivative and a suitable carrier. The composition is topically applied to the skin to reduce the risk of photoaging and improve skin repair due to damage from radiation.

Abstract: A method that uses the transmission spectrum of an opthalmic lens to generate, as output, the ratio of the average transmission of sunlight that repairs the retina to the average transmission of sunlight that causes damage to the retina. This ratio is compared with a similar ratio for the naked eye that correlates with macular degeneration and allows the user to select a ratio that extends the risk of acquiring macular degeneration by multiples of an average lifetime.

Abstract: According to the present invention, light filters are disclosed that provide photoprotection and contain fluorescent agents that have fluorescence emission in the near infrared region of wavelengths to effect photobiological modulation (PBM) of human cells when the cells are exposed to sunlight or any artificial lighting. The fluorescent agents include endogenous compounds. The light filters include ophthalmic lenses, skin care products with or without transparent substrate and any products that are used to filter light. When used in connection with ophthalmic lenses, the ophthalmic lense provides photoprotection and photobiological modulation to the human eye.

Abstract: Ophthalmic lenses and light filters containing special additives that have fluorescence emission in the near infrared region of wavelengths—in order to enhance phototherapy for the human eye when it is exposed to sunlight and artificial lighting.

Abstract: Ophthalmic lenses and light filters containing special additives that have fluorescence emission in the near infrared region of wavelengths—in order to enhance phototherapy for the human eye when it is exposed to sunlight and artificial lighting.

Abstract: A compound, composition, and method for the protection of skin from the harmful effects of radiation, and particularly the harmful effects of high energy visible (HEV) radiation, are disclosed. The compound is a melanin derivative that can be formulated into compositions containing the melanin derivative and a suitable carrier. The composition is topically applied to the skin to reduce the risk of photoaging and improve skin repair due to damage from radiation.

Abstract: A light filter that utilizes UV and visible light-absorbing dyes with transmission spectra in accord with the action spectra for suppression of melatonin so as to permit a maximum production of melatonin in humans during night time exposure to high energy visible light.

Abstract: This invention relates to the use of light filters, for example sunglass lenses, that have transmission spectra characteristic of the pigment found in the human ocular lens and that correspond to different age groups and different darkness.

Abstract: Fluorescence as a new source of haze caused by the light-filtering agent in ophthalmic lenses is introduced. A transparent ophthalmic lens comprising melanin as the light filtering agent with reduced fluorescence from melanin is described and the techniques used to quench the melanin fluorescence.

Abstract: A compound, composition, and method for the protection of skin from the harmful effects of radiation, and particularly the harmful effects of high energy visible (HEV) radiation, are disclosed. The compound is a melanin derivative that can be formulated into compositions containing the melanin derivative and a suitable carrier. The composition is topically applied to the skin to reduce the risk of photoaging and improve skin repair due to damage from radiation.

Abstract: Selective fractionation and separation of melanin and use of fractionated or separated melanin in connection with light filters is disclosed. Further, light filters that use yellow melanin or melanin like materials prepared to have a yellow color and a melanin transmission spectrum in combination with a photochromic dye are disclosed. The yellow form of melanin has minimal impact on the perception of light intensity with transmission values greater than 80%. The combination allows for a single light filter suitable for both night driving and sunglass applications and which also preserve color perception.

Abstract: Light filters that use yellow melanin or melanin like materials prepared to have a yellow color and a melanin transmission spectrum in combination with a photochromic dye are disclosed. The yellow form of melanin has minimal impact on the perception of light intensity with transmission values greater than 80%. The combination allows for a single light filter suitable for both night driving and sunglass applications and which also preserve color perception.

Abstract: The present invention is directed to a transparent medium incorporating the oxidative polymerization of 3-hydroxykynurenine, a synthetic version of the yellow-to-brown pigment that occurs in the ocular crystalline lens with age. Because this coloration in the ocular lens is believed to offer photoprotection to the retina, it may represent an ideal sun lens filter with an optical transmission spectrum that is compatible with the psychophysical and neuro-physiological characteristics of the vision system.

Abstract: A hydrophilic contact lens is disclsoed incorporating melanin that protects the eye from harmful radiation and superoxide.

Abstract: A hydrophilic contact lens is disclosed incorporating melanin that protects the eye from harmful radiation and superoxide.

Abstract: The present invention is directed to a medium incorporating melanin for radiation protection.