Abstract: Compounds that inhibit CNKSR1, pharmaceutical compositions including compounds that inhibit CNKSR1 and methods of treating disease or disorders that respond to CNKSR1 inhibition are described herein. Additionally, methods of identifying inhibitors of CNKSR1 are described.

Abstract: Embodiments include compositions and methods of inhibiting CNKSR1 and methods of identifying inhibitors of CNKSR1.

Abstract: The invention concerns a prosthetic mounting clip (1) having a monolithic structure, made of a biologically absorbable plastic material, comprising a distal anchoring element (2) in an anatomical support (8), a proximal stop element (3) relative to a prosthetic part (9), and a connecting rod (4) linking the distal anchoring element (2) and the proximal stop element (3), the connecting rod (4) being arranged relative to the distal anchoring element (2), to determine at least two positions of said connecting rod (4), namely an inoperative position wherein the connecting rod (4) is arranged along a direction (R) relative to the distal anchoring element (2), and another stressed position wherein the connecting rod (4) is folded back against the distal anchoring element (2) along a second direction (P).