Patents Assigned to Phylonix Pharmaceuticals, Inc.
  • Methods of screening agents for activity using teleosts
    Patent number: 7041276
    Abstract: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: May 9, 2006
    Assignee: Phylonix Pharmaceuticals, Inc.
    Inventors: George N. Serbedzija, Carlos Semino, Deanna Frost
  • Methods of screening agents for activity using teleosts
    Publication number: 20050188426
    Abstract: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. The invention further provides high throughput methods of screening agents in multi-well plates.
    Type: Application
    Filed: April 25, 2005
    Publication date: August 25, 2005
    Applicant: Phylonix Pharmaceuticals, Inc.
    Inventors: George Serbedzija, Carlos Semino, Deanna Frost
  • Methods for introducing heterologous cells into fish to determine if the heterologous cells contain cancer cells or a pathogen
    Publication number: 20040185431
    Abstract: The invention provides methods of introducing heterologous cells into fish. After introduction cells remain viable, and in some instances proliferate, for sufficient time to conduct a variety of analyses on the heterologous cells or the fish or both. Such methods are useful for screening potential drugs for toxicity toward introduced cells or for capacity to stimulate differentiation and/or proliferation of introduced cells. Such methods are also useful for diagnosing the presence of small quantities of cancerous cells or pathogens in patient tissue samples. Such methods are also useful for culturing cells for subsequent use in cell or tissue engineering.
    Type: Application
    Filed: January 27, 2004
    Publication date: September 23, 2004
    Applicant: Phylonix Pharmaceuticals, Inc.
    Inventors: George N. Serbedzija, Patricia McGrath
  • Methods for introducing helterologous cells into fish
    Patent number: 6761876
    Abstract: The invention provides methods of introducing heterologous cells into fish. After introduction cells remain viable, and in some instances proliferate, for sufficient time to conduct a variety of analyses on the heterologous cells or the fish or both. Such methods are useful for screening potential drugs for toxicity toward introduced cells or for capacity to stimulate differentiation and/or proliferation of introduced cells. Such methods are also useful for diagnosing the presence of small quantities of cancerous cells or pathogens in patient tissue samples. Such methods are also useful for culturing cells for subsequent use in cell or tissue engineering.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: July 13, 2004
    Assignee: Phylonix Pharmaceuticals, Inc.
    Inventors: George N. Serbedzija, Carlos E. Semino, Patricia McGrath
  • Methods of screening agents for activity using teleosts
    Publication number: 20040062712
    Abstract: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. The invention further provides high throughput methods of screening agents in multi-well plates.
    Type: Application
    Filed: October 2, 2003
    Publication date: April 1, 2004
    Applicant: Phylonix Pharmaceuticals, Inc.
    Inventors: George N, Serbedzija, Carlos Semino, Deanna M. Frost
  • Methods of screening agents for activity using teleosts
    Patent number: 6656449
    Abstract: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. The invention further provides high throughput methods of screening agents in multi-well plates.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: December 2, 2003
    Assignee: Phylonix Pharmaceuticals, Inc.
    Inventors: George Serbedzija, Wen Lin Seng, Patricia McGrath
  • Methods of screening agents for activity using teleosts
    Patent number: 6299858
    Abstract: The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: October 9, 2001
    Assignee: Phylonix Pharmaceuticals, Inc.
    Inventors: George N. Serbedzija, Carlos Semino, Deanna Frost