Patents Assigned to Phylos Bioscience
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Publication number: 20250137075Abstract: Provided herein is the identification of the causal gene KR associated with THCV, THCVA, CBDV, CBDVA, CBGV, CBGVA, CBCV, or CBCVA production in Cannabis plants. Also included are isolated cells, nucleic acids, transgenic Cannabis plants; methods of editing, and methods of using marker assisted selection to select and establish plant lines having modified THCV, THCVA, CBDV, CBDVA, CBGV, CBGVA, CBCV, or CBCVA activity.Type: ApplicationFiled: August 4, 2022Publication date: May 1, 2025Applicant: Phylos Bioscience, Inc.Inventors: Erica Bakker, Alisha Holloway, Annie Poczynek
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Publication number: 20250127104Abstract: Provided herein is the identification of genetic markers associated with modified cannabinoids relating to levels or ratios of one or more of tetrahydrocannabinol (THC), cannabidiol (CBD), cannabigerol (CBG), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromene (CBC), or cannabigerovarin (CBGV). The markers are useful for breeding plants having modified cannabinoids by obtaining nucleic acids, detecting one or more markers that indicate modified cannabinoids, and establishing plant lines having such characteristics.Type: ApplicationFiled: September 28, 2022Publication date: April 24, 2025Applicant: Phylos Bioscience, Inc.Inventors: Erica Bakker, Alisha Holloway
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Patent number: 12203081Abstract: Provided herein is the identification and use of the Cannabis Ubiquitin promoter and its use in promoting the expression of one or more heterologous nucleic acid fragments in a constitutive manner in Cannabis plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, plants and seeds containing the recombinant construct with the promoter, and methods for preparing and using the same.Type: GrantFiled: October 9, 2020Date of Patent: January 21, 2025Assignee: Phylos Bioscience, Inc.Inventors: Gregory Peel, Kayla Hardwick, Jessica Staha, Alisha Holloway
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Publication number: 20240381800Abstract: A new and distinct variety of Cannabis sativa designated ‘PTC8506V’ as herein described and illustrated, characterized by elevated levels of THCV and THC.Type: ApplicationFiled: April 23, 2024Publication date: November 14, 2024Applicant: Phylos Bioscience, Inc.Inventor: Jared Reynbery
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Publication number: 20240341254Abstract: The present invention discloses Cannabis plants, seeds and other plant parts, tissue cultures, and products having elevated levels of varin molecules, including tetrahydrocannabivarin (THCV) and/or cannabidivarin (CBDV). Each of THCV and CBDV have unique pharmacological profiles with distinct molecular targets, and can be used as agents for antiepileptic or anticonvulsant activity, obesity-associated glucose intolerance, appetite suppression, anxiety management for PTSD, diabetic neuropathy, or major neuropathic and pain related pathologies.Type: ApplicationFiled: October 12, 2022Publication date: October 17, 2024Applicant: Phylos Bioscience, Inc.Inventors: Jared Reynbery, Erica Bakker, John McFerson, Alisha Holloway
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Patent number: 12024712Abstract: Provided herein is the identification and markers and genes associated with day-neutral autoflowering in plants and their use in selecting plants, including Cannabis plants, having autoflowering activity. The markers are useful for breeding autoflowering plants by obtaining nucleic acids, detecting one or more markers that indicate autoflowering activity, and establishing plant lines having such characteristics. Also provided are methods of editing plants to establish plant lines having autoflowering allelic variations.Type: GrantFiled: February 5, 2022Date of Patent: July 2, 2024Assignee: Phylos Bioscience, Inc.Inventors: Erica Bakker, Alisha Holloway, Kristen Waterman
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Publication number: 20240117450Abstract: Provided herein is the identification of markers and genes associated with powdery mildew susceptibility and resistance in Cannabis. The markers are useful for breeding Cannabis plants having resistance to powdery mildew, and methods for selecting plants by obtaining nucleic acids and detecting one or more markers that indicate resistance to powdery mildew to establish plant lines having such resistance are provided.Type: ApplicationFiled: February 4, 2022Publication date: April 11, 2024Applicant: Phylos Bioscience, Inc.Inventors: Erica Bakker, Alisha Holloway
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Patent number: 11920187Abstract: Provided herein is the identification of markers associated with THCV, THCVA, CBDV, CBDVA, CBGV, or CBGVA production in Cannabis plants and their use in selecting Cannabis plants having modified THCV, THCVA, CBDV, CBDVA, CBGV, or CBGVA activity. The markers are useful for breeding plants having modified varin activity, including elevated THCV levels, by obtaining nucleic acids, detecting one or more markers that indicate modified varin activity, and establishing plant lines having such characteristics.Type: GrantFiled: August 24, 2022Date of Patent: March 5, 2024Assignee: Phylos Bioscience, Inc.Inventors: Erica Bakker, Alisha Holloway, Kayla Hardwick
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Publication number: 20230255159Abstract: The present invention discloses cannabis plants, seeds and other plant parts, tissue cultures, and products having elevated levels of varin molecules, including tetrahydrocannabivarin (THCV) and/or cannabidivarin (CBDV). Each of THCV and CBDV have unique pharmacological profiles with distinct molecular targets, and can be used as agents for antiepileptic or anticonvulsant activity, obesity-associated glucose intolerance, appetite suppression, anxiety management for PTSD, diabetic neuropathy, or major neuropathic and pain related pathologies.Type: ApplicationFiled: July 9, 2021Publication date: August 17, 2023Applicant: Phylos Bioscience, Inc.Inventors: Alisha Holloway, Jared Reynbery, Kayla Hardwick, John McFerson, Nishan Karassik, Erica Bakker
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Publication number: 20230242932Abstract: Provided herein is the identification and markers and genes associated with day-neutral autoflowering in plants and their use in selecting plants, including Cannabis plants, having autoflowering activity. The markers are useful for breeding autoflowering plants by obtaining nucleic acids, detecting one or more markers that indicate autoflowering activity, and establishing plant lines having such characteristics. Also provided are methods of editing plants to establish plant lines having autoflowering allelic variations.Type: ApplicationFiled: February 5, 2022Publication date: August 3, 2023Applicant: PHYLOS BIOSCIENCE, INC.Inventors: Erica Bakker, Alisha Holloway, Kristen Waterman
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Patent number: 11240978Abstract: The present invention discloses a hemp plant variety designated NBS CBD-1. The cultivar is a feminized, autoflowering, high CBD hemp variety. The plant and products thereof can be useful for a variety of medicinal uses, including movement disorders, anxiety, and pain, as well as a variety of industrial uses. Also provided are tissues cultures, seeds, and plant cells of the NBS CBD-1 variety.Type: GrantFiled: June 24, 2020Date of Patent: February 8, 2022Assignee: Phylos Bioscience, Inc.Inventor: Harold Frazier
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Publication number: 20200329658Abstract: The present invention discloses a hemp plant variety designated NBS CBD-1. The cultivar is a feminized, autoflowering, high CBD hemp variety. The plant and products thereof can be useful for a variety of medicinal uses, including movement disorders, anxiety, and pain, as well as a variety of industrial uses. Also provided are tissues cultures, seeds, and plant cells of the NBS CBD-1 variety.Type: ApplicationFiled: June 24, 2020Publication date: October 22, 2020Applicant: Phylos BioscienceInventor: Harold Frazier
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Patent number: PP35172Abstract: A new and distinct variety of Cannabis sativa designated ‘PCT11204V’ as herein described and illustrated, characterized by elevated levels of THCV and other varin cannabinoids.Type: GrantFiled: March 11, 2022Date of Patent: May 16, 2023Assignee: Phylos Bioscience, Inc.Inventors: Jared Reynbery, Alisha Holloway, Erica Bakker, John McFerson
