Abstract: A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
Type:
Grant
Filed:
November 15, 2010
Date of Patent:
July 5, 2011
Assignee:
Phytex, LLC
Inventors:
Douglas M. Webel, Donald E. Orr, Jr., Frank E. Ruch, Jr., Xingen Lei
Abstract: A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
Type:
Grant
Filed:
December 21, 2007
Date of Patent:
November 16, 2010
Assignees:
Phytex, LLC, Cornell Research Foundation, Inc.
Inventors:
Douglas M. Webel, Donald E. Orr, Jr., Frank E. Ruch, Jr., Xingen Lei
Abstract: A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
Type:
Grant
Filed:
October 31, 2002
Date of Patent:
January 22, 2008
Assignees:
Phytex, LLC, Cornell Research Foundation, Inc.
Inventors:
Douglas M. Webel, Donald E. Orr, Jr., Frank E. Ruch, Jr., Xingen Lei