Abstract: The invention provides compositions comprising uscharin and the use of uscharin to combat cell proliferation for example in the treatment of cancer. Administration of uscharin may kill or reduce the growth rate of cancer cells and may also be of application in other medical conditions presenting symptoms of excessive or uncontrolled cell proliferation. The composition may be administered by any convenient route and formulated accordingly. The composition may be administered locally or generally and may be suitably dissolved and/or suspended in a pharmaceutically acceptable liquid carrier medium.