Patents Assigned to Phyton Biotech, Inc.
  • Use of indanoyl amide to stimulate secondary metabolism in Taxus sp.
    Publication number: 20050221456
    Abstract: The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp. in a nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stream at any time of the culturing. In particular, synthetic compounds 6-Ethyl-indanoyl-isoleucine, 6-Bromoindanoyl isoleucine and 1-oxo-indane-carboxy-(L)-Isoleucine-methyl ester amide (1-OII) have been found to increase taxane production from Taxus cell cultures.
    Type: Application
    Filed: February 14, 2005
    Publication date: October 6, 2005
    Applicant: Phyton Biotech, Inc.
    Inventors: Venkatesh Srinivasan, Jennifer Alford, Harald Heckenmuller, Braden Roach