Abstract: The present invention discloses that vertebrate viruses encode RNA silencing suppressors/expressional enhancers which enable them to overcome host intracellular defense responses. This has paved the way for the development of protein production systems and for production systems of (recombinant) virus particles, and of vaccines directed against vertebrate viruses.
Type:
Application
Filed:
April 15, 2005
Publication date:
November 24, 2005
Applicant:
Phytovation B.V.
Inventors:
Marinus Prins, Robert Goldbach, Petrus de Haan, Gerrit van Holst