Abstract: Ungulate animals and offspring thereof comprising at least one modified chromosomal sequence in at least one gene encoding an ANP32 protein (e.g., a gene encoding an ANP32A protein or an ANP32B protein) are provided. Ungulate cells that contain such modified chromosomal sequences are also provided. The animals, offspring, and cells have increased resistance to type A influenza viruses. Methods for producing pathogen-resistant ungulate animals or lineages of ungulate animals are also provided.
Abstract: Methods for determining the KIT genotype of pigs are provided. These methods are useful in determining coat colour genotype, breed determination and for screening pigs to determine those likely to produce larger litters, and/or those less likely to produce large litters. Kits for use in such methods are also provided.
Type:
Grant
Filed:
April 24, 2002
Date of Patent:
May 13, 2008
Assignee:
Pig Improvement Company UK, Limited
Inventors:
Leif Andersson, Elisabetta Giuffra, Graham Stuart Plastow, Olwen Irene Southwood
Abstract: The present invention provides methods for analysing animal products. In particular methods for differentiating animal products on the basis of breed origin or validating an animal product are provided.
Type:
Grant
Filed:
January 16, 2004
Date of Patent:
October 23, 2007
Assignee:
Pig Improvement Company UK Limited
Inventors:
Leif Andersson, James Kijas, Elisabetta Giuffra, Gary Jon Evans, Richard Wales, Graham Stuart Plastow
Abstract: Disclosed herein are embodiments to screen an animal for the presence or absence of polymorphisms in the following gene: CKM, SCN4?, and LDH?.
Type:
Application
Filed:
August 24, 2006
Publication date:
January 4, 2007
Applicants:
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC., PIG IMPROVEMENT COMPANY UK LIMITED
Inventors:
Max Rothschild, Stefan Marklund, Richard Robson, Ted Huiatt, Jeannine Helm, Tun-Ping Yu, Graham Plastow
Abstract: Disclosed herein are genetic markers for animal litter size, methods for identifying such markers, and methods of screening animals to determine those more likely to produce larger litters and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the prolactin receptor gene.
Type:
Grant
Filed:
July 6, 2001
Date of Patent:
July 25, 2006
Assignees:
Iowa State University Research Foundation, Inc., PIG Improvement Company UK Limited
Inventors:
Max F. Rothschild, Amy L. Vincent, Christopher K. Tuggle, Christy Gladney, Alan Mileham, Olwen Southwood, Graham Plastow, Carole Sargent
Abstract: Methods are provided for screening pigs to determine those more likely to produce larger litters. The screening method detects the presence of particular alleles in the genome, and in a preferred embodiment, the screening is performed by nucleic acid analysis. Specific primers as well as kits for carrying out the methods of the invention are also provided.