Abstract: This invention relates to a recombinant vector including a recombinant porcine adenovirus, stably incorporating and capable of expression of at least one heterologous nucleotide sequence. The nucleotide sequence is preferably one which encodes an antigenic determinant of Hog Cholera Virus or Pseudorabies virus. The further invention relates to a method of production of recombinant vectors, to methods of preparation of vaccines based on the vectors, to administration strategies and to methods of protecting pigs from disease.
Type:
Application
Filed:
August 22, 2008
Publication date:
September 10, 2009
Applicants:
Commonwealth Scientific and Industrial Research Organisation, Pig Research Development Corporation
Inventors:
Michael A. Johnson, Jeffrey Michael Hammond, Richard J. McCoy, Michael G. Sheppard
Abstract: This invention relates to a recombinant vector including a recombinant porcine adenovirus, stably incorporating and capable of expression of at least one heterologous nucleotide sequence. The nucleotide sequence is preferably one which encodes an antigenic determinant of Hog Cholera Virus or Pseudorabies virus. The further invention relates to a method of production of recombinant vectors, to methods of preparation of vaccines based on the vectors, to administration strategies and to methods of protecting pigs from disease.
Type:
Application
Filed:
March 22, 2006
Publication date:
November 23, 2006
Applicants:
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, PIG RESEARCH DEVELOPMENT CORPORATION
Inventors:
Michael Johnson, Jeffrey Hammond, Richard McCoy, Michael Sheppard
Abstract: The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia intracellularis or similar or otherwise related microorganism. In particular, the present invention provides a novel gene derived from Lawsonia intracellularis which encodes an immunogenic hemolysin peptide, polypeptide or protein that is particularly useful as an antigen in vaccine preparation for conferring humoral immunity against Lawsonia intracellularis and related pathogens in animal hosts. The present invention is also directed to methods for the treatment and/or prophylaxis of such intestinal disease conditions and to diagnostic agents and procedures for detecting Lawsonia intracellularis or similar or otherwise related microorganisms.
Type:
Grant
Filed:
May 11, 2000
Date of Patent:
April 18, 2006
Assignees:
Pfizer Products, Inc., Agriculture Victoria Services Pty. Ltd., Pig Research and Development Corporation
Inventors:
Michael Panaccio, Everett Lee Rosey, Detlef Hasse, Robert Gerard Ankenbauer
Abstract: An expression construct is disclosed which is useful for delivering mature somatotropin to a host. Mature somatotropin is operably linked to an insulin secretory signal. Host cells comprising the expression cassette are cultured under conditions enabling the expression and secretion of somatotropin.
Type:
Grant
Filed:
October 18, 1999
Date of Patent:
November 22, 2005
Assignees:
Commonwealth Scientific and Industrial Research Organisation, University of Western Sydney (Nepean), Pig Research and Development Corporation
Inventors:
Mitchell Keegan, Mark Richard Jones, Geoffrey Philip M. Moore
Abstract: Disclosed herein is a modified microorganism which produces an RTX toxin, wherein said RTX toxin is partially or fully inactivated. Also disclosed is a modified microorganism wherein an RTX toxin gene including an RTX structural gene and/or a post-translational activator of the organism is partially or full inactivated. As disclosed, the precursor of an RTX toxin has reduced toxic activity.
Type:
Grant
Filed:
June 19, 1998
Date of Patent:
October 29, 2002
Assignees:
Commonwealth Scientific and Industrial Research
Organisation, Pig Research and Development Corporation
Inventors:
Christopher Thomas Prideaux, Adrian Leslie Mark Hodgson
Abstract: The present invention provides methods of producing animals that have higher than average carcass quality, higher than average feed conversion efficiency, higher than average growth rate, lower than average voluntary feed intake and/or higher than average reproductive capacity.
Type:
Grant
Filed:
February 2, 1998
Date of Patent:
July 18, 2000
Assignees:
Bunge Meat Industries Ltd., Pig Research and Development Corporation, Gropep PTY Ltd.
Inventors:
Phillip Clyde Owens, Roger Gregory Campbell, Brian Gerard Luxford, Paul Edward Walton